Abstract
Retinoids have been investigated for their therapeutic potential for the past 3 decades. They have a reputation for being both beneficial in the treatment of several diseases and detrimental due to toxic and/or teratogenic side effects. The purpose of this review is to highlight retinoids that are currently used in the clinic. We also discuss their mechanisms of action and research strategies to develop new and safer retinoid-based therapies.
Keywords: Retinoids, rexinoids, retinoic acid metabolism blocking agents (RAMBAs), RAR/RXR, clinical utility
Medicinal Chemistry
Title: Retinoids in Clinical Use
Volume: 2 Issue: 4
Author(s): Vincent C. O. Njar, Lalji Gediya, Puranik Purushottamachar, Panka Chopra, Aashvini Belosay and Jyoti B. Patel
Affiliation:
Keywords: Retinoids, rexinoids, retinoic acid metabolism blocking agents (RAMBAs), RAR/RXR, clinical utility
Abstract: Retinoids have been investigated for their therapeutic potential for the past 3 decades. They have a reputation for being both beneficial in the treatment of several diseases and detrimental due to toxic and/or teratogenic side effects. The purpose of this review is to highlight retinoids that are currently used in the clinic. We also discuss their mechanisms of action and research strategies to develop new and safer retinoid-based therapies.
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Cite this article as:
Njar C. O. Vincent, Gediya Lalji, Purushottamachar Puranik, Chopra Panka, Belosay Aashvini and Patel B. Jyoti, Retinoids in Clinical Use, Medicinal Chemistry 2006; 2 (4) . https://dx.doi.org/10.2174/157340606777724022
DOI https://dx.doi.org/10.2174/157340606777724022 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
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