Generic placeholder image

Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

An Evolving Role of Piperazine Moieties in Drug Design and Discovery

Author(s): Rahul V. Patel and Se Won Park

Volume 13, Issue 11, 2013

Page: [1579 - 1601] Pages: 23

DOI: 10.2174/13895575113139990073

Price: $65

conference banner
Abstract

This article purposes to provide insights to piperazine based molecular designs that will facilitate drug discovery program in future. In our pursuit to summarize the reservoir of bioactive agents, and in line with the synthetic economy of new heterocycles, many new roles are being identified for the multiple biotargets of piperazine moieties. We mark out how series of different scaffolds provide an extensive range of various piperazine-based analogues displaying antimicrobial, antituberculosis, anticancer, antiviral and antimalarial activities. We believe that piperazine family of compounds, and their various co-components, highlight the existence of several potential leads for the furtherance of novel bioactive agents.

Keywords: Piperazine, Antimicrobial activity, antituberculosis activity, anticancer activity, antiviral activity, antimalarial activity.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy