The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy

Title: The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy

Volume: 19 Issue: 6

Author(s): L. E. Xodo, V. Rapozzi, M. Zacchigna, S. Drioli and S. Zorzet

Affiliation:

Keywords: Photodynamic therapy, Pheophorbide a, Photophysical parameters, Tissue distribution, Imaging, In vivo activity, clorophyll, phototoxicity, PDT activity, photochemical reaction

Abstract: Pheophorbide a is a clorophyll catabolite that recently has drawn the attention of several investigators for its potential in photodynamic therapy. In this review we summarize its photophysical properties, phototoxicity, cellular localization, biodistribution and PDT activity as a free or conjugated molecule.

Cite this article as:

E. Xodo L., Rapozzi V., Zacchigna M., Drioli S. and Zorzet S., The Chlorophyll Catabolite Pheophorbide a as a Photosensitizer for the Photodynamic Therapy, Current Medicinal Chemistry 2012; 19 (6) . https://dx.doi.org/10.2174/092986712799034879