Abstract
Organosilicon compounds are important transmetallation reagents in organic synthesis. Aryltrialkoxysilane have recently emerged as an attractive alternative to traditional organometallic donors, due to their ease of handling, stability toward air/moisture, and/or low toxicity compared to some of the other organometallic reagents (Zn, Mg, Sn, etc.). In this review, the application of aryl trialkoxysilane and alkenyltrialkoxysilane as transmetallation reagent for C-C, C-N, C-S and C-O bonds formation will be disclosed.
Keywords: Organosilicon, transmetallation reagent, organic synthesis, organostannanes, Hiyama Reaction, arylsiloxane, -substituted ketones, aldehydes, esters, nitriles, nitroalkanes, enamide derivatives, trialkoxysilane, trialkoxysilanes
Current Organic Chemistry
Title: The Application of Trialkoxysilane as Transmetallation Reagent in Organic Synthesis
Volume: 15 Issue: 16
Author(s): Fang Luo, Changduo Pan and Jiang Cheng
Affiliation:
Keywords: Organosilicon, transmetallation reagent, organic synthesis, organostannanes, Hiyama Reaction, arylsiloxane, -substituted ketones, aldehydes, esters, nitriles, nitroalkanes, enamide derivatives, trialkoxysilane, trialkoxysilanes
Abstract: Organosilicon compounds are important transmetallation reagents in organic synthesis. Aryltrialkoxysilane have recently emerged as an attractive alternative to traditional organometallic donors, due to their ease of handling, stability toward air/moisture, and/or low toxicity compared to some of the other organometallic reagents (Zn, Mg, Sn, etc.). In this review, the application of aryl trialkoxysilane and alkenyltrialkoxysilane as transmetallation reagent for C-C, C-N, C-S and C-O bonds formation will be disclosed.
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Cite this article as:
Luo Fang, Pan Changduo and Cheng Jiang, The Application of Trialkoxysilane as Transmetallation Reagent in Organic Synthesis, Current Organic Chemistry 2011; 15 (16) . https://dx.doi.org/10.2174/138527211796378514
DOI https://dx.doi.org/10.2174/138527211796378514 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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