Abstract
In recent years the diterpene isosteviol, obtained via acid catalyzed rearrangement of stevioside, has gained growing interest by scientists. Its structural features and easy accessibility make isosteviol a useful starting material in organic synthesis. In this review, we group all existing modifications to the isosteviol moiety, ranging from biological transformation to rearrangements of the terpene skeleton. We will also discuss the known macrocycles based on isosteviol
Keywords: Derivatisation, diterpene, hydroxylation, isosteviol, rearrangements, stevioside, supramolecular, ringtransformation, aglycones, diterpene derivatives, steviol, stevia glycosides, stereoselectivities
Current Organic Chemistry
Title: Isosteviol as a Starting Material in Organic Synthesis
Volume: 15 Issue: 15
Author(s): Nico Moons, Wim De Borggraeve and Wim Dehaen
Affiliation:
Keywords: Derivatisation, diterpene, hydroxylation, isosteviol, rearrangements, stevioside, supramolecular, ringtransformation, aglycones, diterpene derivatives, steviol, stevia glycosides, stereoselectivities
Abstract: In recent years the diterpene isosteviol, obtained via acid catalyzed rearrangement of stevioside, has gained growing interest by scientists. Its structural features and easy accessibility make isosteviol a useful starting material in organic synthesis. In this review, we group all existing modifications to the isosteviol moiety, ranging from biological transformation to rearrangements of the terpene skeleton. We will also discuss the known macrocycles based on isosteviol
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Cite this article as:
Moons Nico, De Borggraeve Wim and Dehaen Wim, Isosteviol as a Starting Material in Organic Synthesis, Current Organic Chemistry 2011; 15 (15) . https://dx.doi.org/10.2174/138527211796367372
DOI https://dx.doi.org/10.2174/138527211796367372 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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