Fluorescence-Functionalized Magnetic Nanocomposites as Tracking and Targeting Systems: Their Preparation and Characterizations

Title: Fluorescence-Functionalized Magnetic Nanocomposites as Tracking and Targeting Systems: Their Preparation and Characterizations

Volume: 7 Issue: 4

Author(s): Xibin Yi, Xiaodong Shen, Sheng Cui, Maohong Fan and Yongmei Li

Affiliation:

Keywords: Multifunctional Microspheres, Fe3O4/SiO2/CMCH/CdTe, Fluorescence, Magnetic, Preparation, Characterizations, Biological applications, Diagnostics application, Tracking, Targeting

Abstract: Based on the electrostatic interaction between carboxymethylated chitosan (CMCH) and negatively charged CdTe quantum dots, and the selective crosslinking of CMCH using glutaraldehyde(GA), we demonstrated the formation of Fe3O4/SiO2/CMCH/CdTe microspheres. The dense silicate shells of Fe3O4 nano-particles (NPs) protect the luminescence quenching from Fe3O4 NPs, so the composite microspheres have great fluorescence and emulative magnetism. These multifunctional fluorescence/magnetic microspheres lead to robust and water dispersible nanoparticle colloidosomes, and should be of great importance for diagnostics application and specific biological applications.

Cite this article as:

Yi Xibin, Shen Xiaodong, Cui Sheng, Fan Maohong and Li Yongmei, Fluorescence-Functionalized Magnetic Nanocomposites as Tracking and Targeting Systems: Their Preparation and Characterizations, Current Nanoscience 2011; 7 (4) . https://dx.doi.org/10.2174/157341311796196781