Abstract
Bitter gourd (Momordica charantia, BG) is both a nutritious and healthy food with a distinctive bitter flavor, and it is also widely exploited in folklore medicine. This review focuses on the efficacies and molecular mechanisms of BG-induced anti-diabetic, anti-HIV, and antitumor activities contributed by over twenty active components. The intent of this review is to provide comprehensive and valuable information for medicinal researchers, drug investigators, clinicians, and even patients with an interest in BG. In conclusion, BG is a cornucopia of health and it deserves in-depth investigations for clinical application in the future.
Keywords: Momordica charantia, tumor, human immunodeficiency virus, diabetes, medicinal application, bitter gourd, metabolic disorders, remedy, hyperglycemia, oxidative stress, triterpenoids, charantosides, glucose tolerance, hypoglycemia, AMPK pathway
Current Molecular Medicine
Title: Bitter Gourd (Momordica charantia) is a Cornucopia of Health: A Review of its Credited Antidiabetic, Anti-HIV, and Antitumor Properties
Volume: 11 Issue: 5
Author(s): E. F. Fang and T. B. Ng
Affiliation:
Keywords: Momordica charantia, tumor, human immunodeficiency virus, diabetes, medicinal application, bitter gourd, metabolic disorders, remedy, hyperglycemia, oxidative stress, triterpenoids, charantosides, glucose tolerance, hypoglycemia, AMPK pathway
Abstract: Bitter gourd (Momordica charantia, BG) is both a nutritious and healthy food with a distinctive bitter flavor, and it is also widely exploited in folklore medicine. This review focuses on the efficacies and molecular mechanisms of BG-induced anti-diabetic, anti-HIV, and antitumor activities contributed by over twenty active components. The intent of this review is to provide comprehensive and valuable information for medicinal researchers, drug investigators, clinicians, and even patients with an interest in BG. In conclusion, BG is a cornucopia of health and it deserves in-depth investigations for clinical application in the future.
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Cite this article as:
F. Fang E. and B. Ng T., Bitter Gourd (Momordica charantia) is a Cornucopia of Health: A Review of its Credited Antidiabetic, Anti-HIV, and Antitumor Properties, Current Molecular Medicine 2011; 11 (5) . https://dx.doi.org/10.2174/156652411795976583
DOI https://dx.doi.org/10.2174/156652411795976583 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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