Peptide-Based Subunit Nanovaccines

Title: Peptide-Based Subunit Nanovaccines

Volume: 8 Issue: 3

Author(s): Mariusz Skwarczynski and Istvan Toth

Affiliation:

Keywords: Subunit vaccine, peptide epitope, nanotechnology, nanoparticles, infectious diseases, Nanovaccine, autoimmunity, lipid carriers, inorganic materials, pathogens

Abstract: Classical vaccines incorporating live or attenuated microorganisms possess several disadvantages and cannot be applied against cancer and some pathogens. Modern vaccines utilizing immunogenic subunits derived from a particular pathogen are able to overcome these obstacles but need a specific delivery system for their efficacy. Nanotechnology has opened a new window into these delivery methodologies. A nano-sized formulation of subunit vaccines has been proven to be very effective in inducing cellular and humoral immune responses. Here, we review a number of peptide vaccine delivery strategies based on nanoparticles composed of polymers, peptides, lipids, and inorganic materials.

Cite this article as:

Skwarczynski Mariusz and Toth Istvan, Peptide-Based Subunit Nanovaccines, Current Drug Delivery 2011; 8 (3) . https://dx.doi.org/10.2174/156720111795256192