Abstract
Protein refolding from unfolded state is usually carried out at low temperature to reduce protein aggregation and proteolytic degradation. This review briefly introduces a unique method for the protein refolding via high temperature, typically at above melting temperature of the protein.
Keywords: Inclusion bodies, protein refolding
Current Pharmaceutical Biotechnology
Title: Thermal-Assisted Refolding: Dilution Folding Initiated at High Temperature
Volume: 11 Issue: 3
Author(s): Kentaro Shiraki and Soichiro Kayano
Affiliation:
Keywords: Inclusion bodies, protein refolding
Abstract: Protein refolding from unfolded state is usually carried out at low temperature to reduce protein aggregation and proteolytic degradation. This review briefly introduces a unique method for the protein refolding via high temperature, typically at above melting temperature of the protein.
Export Options
About this article
Cite this article as:
Shiraki Kentaro and Kayano Soichiro, Thermal-Assisted Refolding: Dilution Folding Initiated at High Temperature, Current Pharmaceutical Biotechnology 2010; 11 (3) . https://dx.doi.org/10.2174/138920110791111988
DOI https://dx.doi.org/10.2174/138920110791111988 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Treatment of Foot Disease in Patients with Type 2 Diabetes Mellitus using Human Umbilical Cord Blood Mesenchymal Stem Cells: Response and Correction of Immunological Anomalies
Current Pharmaceutical Design The Urocortins: Mechanisms of Cardioprotection and Therapeutic Potential
Mini-Reviews in Medicinal Chemistry Cytokines in the Central Nervous System: Targets for Therapeutic Intervention
Current Drug Targets - CNS & Neurological Disorders Expression and Function of PPARs in Cancer Stem Cells
Current Stem Cell Research & Therapy JAK Inhibitors: Pharmacology and Clinical Activity in Chronic Myeloprolipherative Neoplasms
Current Medicinal Chemistry Can Increased Food Intake Improve Psychosis? A Brief Review and Hypothesis
Current Molecular Pharmacology Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes
Current Pharmaceutical Design Vitamin D - Pivotal Nutraceutical in the Regulation of Cancer Metastasis and Angiogenesis
Current Medicinal Chemistry Immunology and Epilepsy: Clinical and Experimental Evidence
Current Immunology Reviews (Discontinued) Chaperone-Assisted Secretion in Bacteria: Protein and DNA Transport <i>via</i> Cell Membranes
Current Proteomics Editorial: Frontier Views in Designing Therapeutic Candidates for Management of Diverse Diseases
Current Pharmaceutical Design The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research
Current Drug Targets Differential Developmental Origin of Arteries: Impact on Angiogenesis and Arteriogenesis
Medicinal Chemistry Reviews - Online (Discontinued) Medicinal and Beneficial Health Applications of Tinospora cordifolia (Guduchi): A Miraculous Herb Countering Various Diseases/Disorders and its Immunomodulatory Effects
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) New Insights on the Possible Role of Mast Cells in Aspirin-Induced Asthma
Current Molecular Pharmacology Synthesis of 2-Thiohydantoins as Somatostatin Subtype 4 Receptor Ligands
Letters in Drug Design & Discovery A Critical and Comprehensive Insight on Heme Oxygenase and Related Products Including Carbon Monoxide, Bilirubin, Biliverdin and Ferritin in Type-1 and Type-2 Diabetes
Current Pharmaceutical Design Correlation Between ROS Production and InsP3 Released by Granulocytes from Type 1 Diabetic Patients in a cAMP-Dependent Manner
Current Aging Science Computationally Probing Drug-Protein Interactions Via Support Vector Machine
Letters in Drug Design & Discovery Early Inflammatory Processes in the Skin
Current Molecular Medicine