Abstract
Compounds with triazepine skeletons have attracted much attention as a result of their interesting biological properties. Triazepandiones represent a particular subset that includes sixteen possible functional isomers, of which nine have been reported in the literature and patents. A survey of the literature indicates that intramolecular cyclization reactions and transformation of other heterocyclic systems are the two main synthetic approaches employed to prepare triazepandiones. This review covers both synthetic methods and applications of compounds with triazepandione skeletons.
Current Organic Chemistry
Title: Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications
Volume: 12 Issue: 10
Author(s): G. Lena and G. Guichard
Affiliation:
Abstract: Compounds with triazepine skeletons have attracted much attention as a result of their interesting biological properties. Triazepandiones represent a particular subset that includes sixteen possible functional isomers, of which nine have been reported in the literature and patents. A survey of the literature indicates that intramolecular cyclization reactions and transformation of other heterocyclic systems are the two main synthetic approaches employed to prepare triazepandiones. This review covers both synthetic methods and applications of compounds with triazepandione skeletons.
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Cite this article as:
Lena G. and Guichard G., Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications, Current Organic Chemistry 2008; 12 (10) . https://dx.doi.org/10.2174/138527208784911879
DOI https://dx.doi.org/10.2174/138527208784911879 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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