Abstract
Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review briefly summarizes the photophysical, photochemical and synthetic aspects of phthalocyanines compounds, evaluating their application for PDT.
Keywords: phthalocyanines, photodynamic therapy, metallo phthalocyanine derivative, pdt
Current Organic Chemistry
Title: Synthesis, Photophysical and Photochemical Aspects of Phthalocyanines for Photodynamic Therapy
Volume: 7 Issue: 2
Author(s): Antonio C. Tedesco, Jeane C. G. Rotta and Claure N. Lunardi
Affiliation:
Keywords: phthalocyanines, photodynamic therapy, metallo phthalocyanine derivative, pdt
Abstract: Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review briefly summarizes the photophysical, photochemical and synthetic aspects of phthalocyanines compounds, evaluating their application for PDT.
Export Options
About this article
Cite this article as:
Tedesco C. Antonio, Rotta C. G. Jeane and Lunardi N. Claure, Synthesis, Photophysical and Photochemical Aspects of Phthalocyanines for Photodynamic Therapy, Current Organic Chemistry 2003; 7 (2) . https://dx.doi.org/10.2174/1385272033373076
DOI https://dx.doi.org/10.2174/1385272033373076 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Aneuploidy-Inducing Mutations in Mitotic Checkpoint Protein hMad1-Carboxi Terminal Domain Analyzed by SAR and Computational Mutagenesis
Current Proteomics The PIK3CA Gene as a Mutated Target for Cancer Therapy
Current Cancer Drug Targets Diagnosis and Management of Heart Failure with Preserved Ejection Fraction: 10 Key Lessons
Current Cardiology Reviews Metabolomics in the Diagnosis and Pharmacotherapy of Lung Diseases
Current Pharmaceutical Design DNA Damage Response Pathways and Cell Cycle Checkpoints in Colorectal Cancer: Current Concepts and Future Perspectives for Targeted Treatment
Current Cancer Drug Targets Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress
Current Drug Targets The Mad2-Binding Protein p31<sup>comet</sup> as a Potential Target for Human Cancer Therapy
Current Cancer Drug Targets Harnessing the Natural Pool of Polyketide and Non-ribosomal Peptide Family: A Route Map towards Novel Drug Development
Current Molecular Pharmacology Cellular and Humoral Responses following Minimally Invasive Surgery: Role of Reactive Oxygen Species
Current Metabolomics Anti-Cancer Effects of Citalopram on Hepatocellular Carcinoma Cells Occur via Cytochrome C Release and the Activation of NF-kB
Anti-Cancer Agents in Medicinal Chemistry Dendritic Cells in Colorectal Cancer and a Potential for their Use in Therapeutic Approaches
Current Pharmaceutical Design Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions
Current Medicinal Chemistry γ-Secretase Substrates and their Implications for Drug Development in Alzheimer's Disease
Current Topics in Medicinal Chemistry Safety Concerns Related to Hematopoietic Stem Cell Gene Transfer Using Retroviral Vectors
Current Gene Therapy The Association of Sleep Disorders, Obesity and Sleep-Related Hypoxia with Cancer
Current Genomics Graphical Abstracts
Anti-Cancer Agents in Medicinal Chemistry Effects of BCR-ABL Inhibitors on Anti-Tumor Immunity
Current Medicinal Chemistry MBD1 is an Epigenetic Regulator of KEAP1 in Pancreatic Cancer
Current Molecular Medicine Modulation of Immuno-biome during Radio-sensitization of Tumors by Glycolytic Inhibitors
Current Medicinal Chemistry Role of Copper in Angiogenesis and Its Medicinal Implications
Current Medicinal Chemistry