Abstract
Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.
Keywords: Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease
Current HIV Research
Title: Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection
Volume: 4 Issue: 1
Author(s): Giuseppe Barbaro
Affiliation:
Keywords: Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease
Abstract: Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.
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Cite this article as:
Barbaro Giuseppe, Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection, Current HIV Research 2006; 4 (1) . https://dx.doi.org/10.2174/157016206775197664
DOI https://dx.doi.org/10.2174/157016206775197664 |
Print ISSN 1570-162X |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4251 |
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