Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

Title: Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

Volume: 4 Issue: 1

Author(s): Giuseppe Barbaro

Affiliation:

Keywords: Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease

Abstract: Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.

Cite this article as:

Barbaro Giuseppe, Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection, Current HIV Research 2006; 4 (1) . https://dx.doi.org/10.2174/157016206775197664