Login Register Cart 0
Generic placeholder image

Current Rheumatology Reviews

Editor-in-Chief

ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Case Report

Association of Large Vessel Aneurysm/Pseudo-Aneurysm/Aortitis and Deep Vein Thrombosis in Patients with Behçet’s Disease: A Case Report

Author(s): Saeedeh Shenavandeh*, Hamed Ghoddusi Johari and Elham Aflaki

Volume 18, Issue 1, 2022

Published on: 20 September, 2021

Page: [83 - 87] Pages: 5

DOI: 10.2174/1573397117666210920154400

Price: $65

Abstract

Background: Behçet’s disease (BD) is a complex vasculitis with some vascular manifestations including venous thrombosis, arterial thrombosis/aneurysm/pseudoaneurysm, and co-associated venous thrombosis and arterial lesions. We present two patients with Behçet’s disease came with progressive both arterial and venous involvement.

Case Presentation: The first patient was a young man with recurrent oral aphthosis and skin folliculitis and referred with complaint of new abdominal pain and 2 months severe headache. He had not referred to a physician due to COVID-19 pandemic until that time. In addition, he gradually developed a lower extremity edema and eventually was diagnosed with BD complicated with brain sagittal sinus vein thrombosis, abdominal aortic aneurysms and aortitis and deep vein thrombosis (DVT) of femoral vein. The second patient was a young woman with previous history of uveitis, DVT and recurrent oral and genital aphthosis presented with a large inguinal mass due to large iliac artery pseudoaneurysm impending to rupture, and after the operation, due to poor follow-up, developed a new femoral DVT.

Conclusion: It seems the same inflammatory process is responsible for arterial and venous involvement in patients with BD, so it should be considered that involvement in one side (venous/arterial) can be a risk factor for the other side (venous/arterial) and early immunosuppressive treatment should always be considered to improve the prognosis.

Keywords: Behçet’s disease, pseudo-aneurysm, deep vein thrombosis, aneurysm, aortitis, COVID-19.

« Previous
[1]
Emmi G, Bettiol A, Silvestri E, et al. Vascular Behçet’s syndrome: an update. Intern Emerg Med 2019; 14(5): 645-52.
[http://dx.doi.org/10.1007/s11739-018-1991-y] [PMID: 30499073]
[2]
Sahutoglu T, Artim Esen B. Clinical course of abdominal aortic aneurysms in Behçet disease: a retrospective analysis. 2019; 39(6): 1061-7.
[http://dx.doi.org/10.1007/s00296-019-04283-y]
[3]
Davatchi F, Shahram F, Chams-Davatchi C, et al. Behcet’s disease in Iran: Analysis of 7641 cases. Mod Rheumatol 2019; 29(6): 1023-30.
[http://dx.doi.org/10.1080/14397595.2018.1558752] [PMID: 30557064]
[4]
Fei Y, Li X, Lin S, et al. Major vascular involvement in Behçet’s disease: a retrospective study of 796 patients. Clin Rheumatol 2013; 32(6): 845-52.
[http://dx.doi.org/10.1007/s10067-013-2205-7] [PMID: 23443336]
[5]
Tascilar K, Melikoglu M, Ugurlu S, Sut N, Caglar E, Yazici H. Vascular involvement in Behçet’s syndrome: a retrospective analysis of associations and the time course. Rheumatology (Oxford) 2014; 53(11): 2018-22.
[http://dx.doi.org/10.1093/rheumatology/keu233] [PMID: 24907156]
[6]
International Team for the Revision of the International Criteria for Behçet’s Disease (ITR-ICBD). The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014; 28(3): 338-47.
[http://dx.doi.org/10.1111/jdv.12107] [PMID: 23441863]
[7]
Hasanaghaei T, Ghoddusi Johari H, Shenavandeh S. Huge femoral artery pseudoaneurysm in a patient with Behçet’s disease. Egypt Rheumatol 2017; 39(4): 267-70.
[http://dx.doi.org/10.1016/j.ejr.2017.02.001]
[8]
Katabathina VS, Restrepo CS. Infectious and noninfectious aortitis: cross-sectional imaging findings. Semin Ultrasound CT MR 2012; 33(3): 207-21.
[http://dx.doi.org/10.1053/j.sult.2011.12.001] [PMID: 22624966]
[9]
Owlia MB, Mehrpoor G. Behcet’s disease: New concepts in cardiovascular involvements and future direction for treatment. ISRN Pharmacol 2012; 2012: 760484.
[http://dx.doi.org/10.5402/2012/760484] [PMID: 22530146]
[10]
Yazici H, Seyahi E, Hatemi G, Yazici Y. Behçet syndrome: a contemporary view. Nat Rev Rheumatol 2018; 14(2): 119.
[http://dx.doi.org/10.1038/nrrheum.2018.3] [PMID: 29362466]
[11]
Uluduz D, Midi I, Duman T, et al. Behçet’s disease as a causative factor of cerebral venous sinus thrombosis: subgroup analysis of data from the VENOST study. Rheumatology (Oxford) 2019; 58(4): 600-8.
[http://dx.doi.org/10.1093/rheumatology/key153] [PMID: 29992235]
[12]
Hosaka A, Miyata T, Shigematsu H, et al. Long-term outcome after surgical treatment of arterial lesions in Behçet disease. J Vasc Surg 2005; 42(1): 116-21.
[http://dx.doi.org/10.1016/j.jvs.2005.03.019] [PMID: 16012460]
[13]
Wong KC, Cheok JWG, Tay KXK, Koh SB, Howe TS. Where have all the hip fractures gone? Osteoporosis international : A journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020; 1-2.

Rights & Permissions Print Cite
Article Metrics
25
1
© 2024 Bentham Science Publishers | Privacy Policy