Abstract
Infectious diseases have been evolving and re-evolving over the ages and causing immense misery to humans. Among them, some have been prevented and eradicated, but few are still threatening the modern era since their origin. The majority of these infectious diseases are poverty-driven, hence highly prevalent in the lower-income and mid-income countries of Africa and Asia. The world’s deadliest infections, including Tuberculosis, Malaria and HIV/AIDS, have been considered as the “Big Three” infectious diseases (BTIDs). With leading infections and deaths every year, the BTIDs have been recognized as the world’s greatest pandemics. In light of these alarming situations, this review has been aimed to provide a comprehensive overview of the current status of chemotherapeutics, associated challenges and future perspectives of BTIDs.
Keywords: “Big Three” infectious diseases, Tuberculosis, Malaria, HIV/AIDS, Chemotherapeutic agents, BTIDs, burden.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:“Big Three” Infectious Diseases: Tuberculosis, Malaria and HIV/AIDS
Volume: 21 Issue: 31
Author(s): Parameshwar Makam*Ramkishore Matsa
Affiliation:
- Chemical Science Research Group, Advanced Research Group, Division of Research and Development, Lovely Professional University, Phagwara, Punjab-144411,India
Keywords: “Big Three” infectious diseases, Tuberculosis, Malaria, HIV/AIDS, Chemotherapeutic agents, BTIDs, burden.
Abstract: Infectious diseases have been evolving and re-evolving over the ages and causing immense misery to humans. Among them, some have been prevented and eradicated, but few are still threatening the modern era since their origin. The majority of these infectious diseases are poverty-driven, hence highly prevalent in the lower-income and mid-income countries of Africa and Asia. The world’s deadliest infections, including Tuberculosis, Malaria and HIV/AIDS, have been considered as the “Big Three” infectious diseases (BTIDs). With leading infections and deaths every year, the BTIDs have been recognized as the world’s greatest pandemics. In light of these alarming situations, this review has been aimed to provide a comprehensive overview of the current status of chemotherapeutics, associated challenges and future perspectives of BTIDs.
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Cite this article as:
Makam Parameshwar *, Matsa Ramkishore, “Big Three” Infectious Diseases: Tuberculosis, Malaria and HIV/AIDS, Current Topics in Medicinal Chemistry 2021; 21 (31) . https://dx.doi.org/10.2174/1568026621666210916170417
DOI https://dx.doi.org/10.2174/1568026621666210916170417 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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