The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review

Title:The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review

Volume: 18 Issue: 11

Author(s): Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh

Affiliation:

• Department of Chemistry, Banasthali University, Banasthali Bansthali-304022,India

Keywords: Combinatorial chemistry, medicinal chemistry, pharmacological activity, pharmacophore, pyrazole, QSAR.

Abstract: Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry. This review presents a detailed overview on the synthesis, QSAR and pharmacological applications of pyrazole. In addition, it covers most recent reports on structural modifications on pyrazole illustrating vital structural activity relationship.

Cite this article as:

Dwivedi Jaya *, Sharma Swapnil , Jain Sonika and Singh Aarti , The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review, Mini-Reviews in Medicinal Chemistry 2018; 18 (11) . https://dx.doi.org/10.2174/1389557517666170927160919