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Current Stem Cell Research & Therapy

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ISSN (Print): 1574-888X
ISSN (Online): 2212-3946

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Review Article

Application of Stem Cell Therapy During the Treatment of HIV/AIDS and Duchenne Muscular Dystrophy

Author(s): Lorraine Chitena, Keletso Masisi, Kabo Masisi, Tebogo E. Kwape and Goabaone Gaobotse*

Volume 17, Issue 7, 2022

Published on: 10 August, 2021

Page: [633 - 647] Pages: 15

DOI: 10.2174/1574888X16666210810104445

Price: $65

Abstract

Treating diseases such as Muscular Dystrophy (MD) and HIV/AIDS pose several challenges to the rapidly evolving field of regenerative medicine. Previously, stem cell therapy has been said to affect the clinical courses of HIV/AIDS and MD, but, in practice, eradication or control of these diseases was not achievable. The introduction of gene editing into stem cell therapy has stimulated HIV/AIDS and MD cell therapy research studies substantially. Here, we review current methods of treating HIV/AIDS and MD using stem cell therapy. This review also details the use of different types of cells and methods in cell therapy and the modeling of new cell-based therapies to treat Duchenne muscular dystrophy. We speculate that the effective use of stem cell therapy in conjunction with other treatment therapies , such as steroids and rehabilitation , could improve livelihood.

Keywords: High active antiretroviral therapy, C-C chemokine receptor 5, antiretroviral treatment, pre-exposure prophylaxis, hematopoietic stem cells, induced pluripotent stem cells, muscular dystrophy, duchenne muscular dystrophy, melancholy stem cells.

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