Abstract
Background: Serratia spp. is a common enteric bacterium generally thought not to be pathogenic in the gastrointestinal tract. Serratia marcescens is a member of the genus Serratia, which is a part of the family Enterobacteriales. Of all Serratia species, S. marcescens is the most common clinical isolate and the most important human pathogen.
Objective: We discuss here four cases of Serratia marcescens which were reported in our laboratory at the Department of Microbiology Government Medical College and Hospital Chandigarh within six months of duration.
Method: All the samples were processed and identified using standard microbiological techniques. The isolates of Serratia marcescens were identified, depending upon their biochemical and morphological characteristics, and further confirmed by MALDI-TOF-MS, PGIMER Chandigarh.
Result: In one of the four cases, polymicrobial infection was observed, and among the cases, one patient was diabetic and the rest three patients were immunocompetent. The importance of detection of Serratia marcescens is related to the concern regarding its increased spread in hospital settings as nosocomial infection.
Conclusion: We need to identify and isolate this pathogen not thinking of it only as a contaminant and opportunistic pathogen but as a pathogen which can lead to serious infections in hospital settings.
Keywords: Serratia marcescens, nosocomial infections, opportunistic pathogen, immunocompetent, antibiotics, Serratia species.
Infectious Disorders - Drug Targets
Title:Serratia, No Longer an Uncommon Opportunistic Pathogen – Case Series & Review of Literature
Volume: 21 Issue: 7
Author(s): Varsha Gupta, Shiwani Sharma*, Kritika Pal, Poonam Goyal, Deepak Agarwal and Jagdish Chander
Affiliation:
- Department of Microbiology, Government Medical College Hospital, Chandigarh,India
Keywords: Serratia marcescens, nosocomial infections, opportunistic pathogen, immunocompetent, antibiotics, Serratia species.
Abstract: Background: Serratia spp. is a common enteric bacterium generally thought not to be pathogenic in the gastrointestinal tract. Serratia marcescens is a member of the genus Serratia, which is a part of the family Enterobacteriales. Of all Serratia species, S. marcescens is the most common clinical isolate and the most important human pathogen.
Objective: We discuss here four cases of Serratia marcescens which were reported in our laboratory at the Department of Microbiology Government Medical College and Hospital Chandigarh within six months of duration.
Method: All the samples were processed and identified using standard microbiological techniques. The isolates of Serratia marcescens were identified, depending upon their biochemical and morphological characteristics, and further confirmed by MALDI-TOF-MS, PGIMER Chandigarh.
Result: In one of the four cases, polymicrobial infection was observed, and among the cases, one patient was diabetic and the rest three patients were immunocompetent. The importance of detection of Serratia marcescens is related to the concern regarding its increased spread in hospital settings as nosocomial infection.
Conclusion: We need to identify and isolate this pathogen not thinking of it only as a contaminant and opportunistic pathogen but as a pathogen which can lead to serious infections in hospital settings.
Export Options
About this article
Cite this article as:
Gupta Varsha, Sharma Shiwani *, Pal Kritika , Goyal Poonam , Agarwal Deepak and Chander Jagdish , Serratia, No Longer an Uncommon Opportunistic Pathogen – Case Series & Review of Literature, Infectious Disorders - Drug Targets 2021; 21 (7) : e300821191666 . https://dx.doi.org/10.2174/1871526521666210222125215
DOI https://dx.doi.org/10.2174/1871526521666210222125215 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Burkholderia mallei and Burkholderia pseudomallei: The Causative Micro-organisms of Glanders and Melioidosis
Recent Patents on Anti-Infective Drug Discovery Nanomedicines as Cancer Therapeutics: Current Status
Current Cancer Drug Targets Occipital Encephalocele: Cause, Incidence, Neuroimaging and Surgical Management
Current Pediatric Reviews Cephalosporins Associated Pseudomembraneous Colitis in an Elderly Male Patient - A Case Report
Current Drug Safety A New Frontier in the Treatment of Cancer: NK-1 Receptor Antagonists
Current Medicinal Chemistry Linezolid in Children: Recent Patents and Advances
Recent Patents on Anti-Infective Drug Discovery The Role of Universal Stress Proteins in Bacterial Infections
Current Medicinal Chemistry Infectious Causes of Childhood Disability
Infectious Disorders - Drug Targets Phosphodiesterase Inhibitors as a Target for Cognition Enhancement in Aging and Alzheimer’s Disease: A Translational Overview
Current Pharmaceutical Design The Role of Bacterial DNA in Inflammatory and Allergic Disease
Recent Patents on Inflammation & Allergy Drug Discovery Allopurinol Hypersensitivity Reactions: Desensitization Strategies and New Therapeutic Alternative Molecules
Inflammation & Allergy - Drug Targets (Discontinued) Neuroprotection and Hypothermia in Infants and Children
Current Drug Targets Syphilis: An Epidemiological Review
Current Women`s Health Reviews Neuroinflammation, Microglia and Mast Cells in the Pathophysiology of Neurocognitive Disorders: A Review
CNS & Neurological Disorders - Drug Targets Tuberculosis Therapeutics: Past Achievements, Present Road-Blocks and Future Perspectives
Letters in Drug Design & Discovery CGRP Receptor Antagonism and Migraine Therapy
Current Protein & Peptide Science Antifungal Agents in Hematopoietic Stem Cell Transplantation
Current Pharmaceutical Design Aminobisphosphonates as New Weapons for γ δ T Cell-Based Immunotherapy of Cancer
Current Medicinal Chemistry Cisternal Sustained Release Dihydropyridines for Subarachnoid Hemorrhage
Current Neurovascular Research Giant Cell Arteritis – A Series of Cases and Review of Literature
Current Rheumatology Reviews