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ISSN (Online): 1873-4316

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Review Article

Role of Medicinal Plants against Neurodegenerative Diseases

Author(s): Ritika Luthra and Arpita Roy*

Volume 23, Issue 1, 2022

Published on: 11 February, 2021

Page: [123 - 139] Pages: 17

DOI: 10.2174/1389201022666210211123539

Price: $65

Abstract

Diseases with a significant loss of neurons, structurally and functionally are termed as neurodegenerative diseases. Due to the present therapeutic interventions and progressive nature of diseases, a variety of side effects have risen up, thus leading the patients to go for an alternative medication. The role of medicinal plants in such cases has been beneficial because of their exhibition via different cellular and molecular mechanisms. Alleviation in inflammatory responses, suppression of the functionary aspect of pro-inflammatory cytokines like a tumor, improvement in antioxidative properties is among few neuroprotective mechanisms of traditional plants. Variation in transcription and transduction pathways plays a vital role in the preventive measures of plants in such diseases. Neurodegenerative diseases are generally caused by the depletion of proteins, oxidative and inflammatory stress, environmental changes and so on, with aging being the most important cause. Natural compounds can be used in order to treat neurodegenerative diseases Medicinal plants such as Ginseng, Withania somnifera, Bacopa monnieri, Ginkgo biloba, etc. are some of the medicinal plants for the prevention of neurological symptoms. This review deals with the use of different medicinal plants for the prevention of neurodegenerative diseases.

Keywords: Neurodegeneration, oxidative stress, inflammatory stress, medicinal plants, phytocompounds, treatment.

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