Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

Title:Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

Volume: 28 Issue: 20

Author(s): Hayati Filik*, Asiye Aslıhan Avan and Mustafa Özyürek

Affiliation:

• Istanbul University-Cerrahpasa, Faculty of Engineering, Department of Chemistry, 34320 Avcilar, Istanbul,Turkey

Keywords: Prostate-specific antigen, cancer marker, immunosensor, immunoassay, nanomaterial, nanotechnology.

Abstract: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This survey shows recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

Cite this article as:

Filik Hayati *, Avan Aslıhan Asiye and Özyürek Mustafa, Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review, Current Medicinal Chemistry 2021; 28 (20) . https://dx.doi.org/10.2174/0929867328666201124151821