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Current Diabetes Reviews

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ISSN (Print): 1573-3998
ISSN (Online): 1875-6417

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Review Article

Endocrine Disruptors and the Induction of Insulin Resistance

Author(s): Rafael Vanni, Renata Maksoud Bussuan, Renato Luiz Rombaldi and Alberto K. Arbex*

Volume 17, Issue 7, 2021

Published on: 22 October, 2020

Article ID: e102220187107 Pages: 14

DOI: 10.2174/1573399816666201022121254

Price: $65

Abstract

Introduction: The incidence of insulin resistance syndrome and type 2 diabetes mellitus has increased at an alarming rate worldwide and constitutes a serious challenge to public health care in the 21st century. Endocrine disrupting chemicals are defined as “substances or mixtures of substances that alter the endocrine system functions and, hence, adversely affect organisms, their progeny, or sub populations” and may be associated with this increase in prevalence.

Objective: This study aimed to assess the role of endocrine disrupting chemicals in insulin resistance and the importance of approaching the subject during anamnesis.

Methods: A full review of the literature regarding insulin resistance, type-2 diabetes and endocrine disruptors were conducted.

Conclusion: Large-scale production and distribution of endocrine disrupting chemicals coincide with the increase in the prevalence of insulin resistance globally. In recent years, studies have shown that endocrine disrupting chemicals are positively associated with insulin resistance syndrome, evidenced by worse prognoses among individuals with higher levels of exposure. Health professionals should recognize the forms of exposure, most susceptible people, and lifestyle habits that can worsen patients’ prognoses.

Keywords: endocrine disruptors, insulin resistance, bisphenol A, obesity, environmental pollutants, anamnesis.

[1]
International diabetes federation. International diabetes federation. IDF Diabetes Atlas. (8th ed.), 2017.
[2]
Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives. Nat Rev Endocrinol 2011; 8(4): 228-36.
[http://dx.doi.org/10.1038/nrendo.2011.183] [PMID: 22064493]
[3]
Thayer KA, Heindel JJ, Bucher JR, Gallo MA. Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review. Environ Health Perspect 2012; 120(6): 779-89.
[http://dx.doi.org/10.1289/ehp.1104597] [PMID: 22296744]
[4]
WORLD HEALTH ORGANIZATION. International Programme for Chemical Safety [IPCS] in Global Assessment of the State-ofthe- science of endocrine disruptorsChapter 1: Executive Summary. 2010; pp. 1-3.
[5]
Song Y, Chou EL, Baecker A, et al. Endocrine-disrupting chemicals, risk of type 2 diabetes, and diabetes-related metabolic traits: A systematic review and meta-analysis. J Diabetes 2016; 8(4): 516-32.
[http://dx.doi.org/10.1111/1753-0407.12325] [PMID: 26119400]
[6]
Casals-Casas C, Desvergne B. Endocrine disruptors: from endocrine to metabolic disruption. Annu Rev Physiol 2011; 73: 135-62.
[http://dx.doi.org/10.1146/annurev-physiol-012110-142200] [PMID: 21054169]
[7]
Vom Saal FS, Nagel SC, Coe BL, Angle BM, Taylor JA. The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity. Mol Cell Endocrinol 2012; 354(1-2): 74-84.
[http://dx.doi.org/10.1016/j.mce.2012.01.001] [PMID: 22249005]
[8]
FLEISCH A. F. WRIGHT R. O. BACCARELLI A. A. Environmental epigenetics: A role in endocrine disease? Mol Endocrinol 2012; 49: R61-7.
[http://dx.doi.org/10.1530/JME-12-0066]
[9]
Kabir ER, Rahman MS, Rahman I. A review on endocrine disruptors and their possible impacts on human health. Environ Toxicol Pharmacol 2015; 40(1): 241-58.
[http://dx.doi.org/10.1016/j.etap.2015.06.009] [PMID: 26164742]
[10]
Lin Y, Wei J, Li Y, et al. Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat. Am J Physiol Endocrinol Metab 2011; 301(3): E527-38.
[http://dx.doi.org/10.1152/ajpendo.00233.2011] [PMID: 21673306]
[11]
WORLD HEALTH ORGANIZATION. State of the science of endocrine disrupting chemicals WORLD HEALTH ORGANIZATION 2012.
[12]
Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, et al. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev 2009; 30(4): 293-342.
[http://dx.doi.org/10.1210/er.2009-0002] [PMID: 19502515]
[13]
Gerald M. REAVEN Role of insulin resistance in human disease. Diabetes 1988; 37(12): 1595-607.
[14]
Norman M. KAPLAN. The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension Archives of internal medicine 1989; 149(7): 1514-20.
[15]
LAKIND J S, et al. . Comparing United State and Canadian population exposures from national biomonitoring surveys: Bisphenol A intake as a case study. Journal of Exposure Science and Environmental Epidemiology 2012; 22: 219-26.
[16]
Indumathi D, Jayashree S, Selvaraj J, et al. Effect of bisphenol-A on insulin signal transduction and glucose oxidation in skeletal muscle of adult male albino rat. Hum Exp Toxicol 2013; 32(9): 960-71.
[http://dx.doi.org/10.1177/0960327112470273] [PMID: 23424204]
[17]
Song S, Zhang L, Zhang H, Wei W, Jia L. Perinatal BPA exposure induces hyperglycemia, oxidative stress and decreased adiponectin production in later life of male rat offspring. Int J Environ Res Public Health 2014; 11(4): 3728-42.
[http://dx.doi.org/10.3390/ijerph110403728] [PMID: 24705360]
[18]
Angle BM, Do RP, Ponzi D, et al. Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation. Reprod Toxicol 2013; 42: 256-68.
[http://dx.doi.org/10.1016/j.reprotox.2013.07.017] [PMID: 23892310]
[19]
Alonso-Magdalena P, García-Arévalo M, Quesada I, Nadal Á. Bisphenol-A treatment during pregnancy in mice: a new window of susceptibility for the development of diabetes in mothers later in life. Endocrinology 2015; 156(5): 1659-70.
[http://dx.doi.org/10.1210/en.2014-1952] [PMID: 25830705]
[20]
Menale C, Grandone A, Nicolucci C, et al. Bisphenol A is associated with insulin resistance and modulates adiponectin and resistin gene expression in obese children. Pediatr Obes 2017; 12(5): 380-7.
[http://dx.doi.org/10.1111/ijpo.12154] [PMID: 27187765]
[21]
Li DK, Miao M, Zhou Z, et al. LI D. et al. Urine bisphenol-A level in relation to obesity and overweight in school-age children. PLoS One 2013; 8(6): e65399.
[http://dx.doi.org/10.1371/journal.pone.0065399] [PMID: 23776476]
[22]
Sabanayagam C, Teppala S, Shankar A. Relationship between urinary bisphenol A levels and prediabetes among subjects free of diabetes. Acta Diabetol 2013; 50(4): 625-31.
[http://dx.doi.org/10.1007/s00592-013-0472-z] [PMID: 23636267]
[23]
Shankar A. Teppala S. Relationship between urinary bisphenol A levels and diabetes mellitus. Clin Endocrinol Metab 2011; 96: 3822-6.
[http://dx.doi.org/10.1210/jc.2011-1682]
[24]
HANNON P. R.. FLAWS J. A. The effects of phthalates on the ovary. Front Endocrinol 2015; 6: 8.
[25]
Marie C, Hamlaoui S, Bernard L, et al. Exposure of hospitalised pregnant women to plasticizers contained in medical devices. BMC Womens Health 2017; 17(1): 45.
[http://dx.doi.org/10.1186/s12905-017-0398-7] [PMID: 28637458]
[26]
Kelley KE, Hernández-Díaz S, Chaplin EL, Hauser R, Mitchell AA. Identification of phthalates in medications and dietary supplement formulations in the United States and Canada. Environ Health Perspect 2012; 120(3): 379-84.
[http://dx.doi.org/10.1289/ehp.1103998] [PMID: 22169271]
[27]
Rajesh P, Balasubramanian K. Di(2-ethylhexyl)phthalate exposure impairs insulin receptor and glucose transporter 4 gene expression in L6 myotubes. Hum Exp Toxicol 2014; 33(7): 685-700.
[http://dx.doi.org/10.1177/0960327113506238] [PMID: 24130215]
[28]
Duan Y, Wang L, Han L, et al. Exposure to phthalates in patients with diabetes and its association with oxidative stress, adiponectin, and inflammatory cytokines. Environ Int 2017; 109: 53-63.
[http://dx.doi.org/10.1016/j.envint.2017.09.002] [PMID: 28938100]
[29]
Cullen E, Evans D, Griffin C, et al. Urinary phthalate concentrations in mothers and their children in Ireland: Results of DEMOCOPHES human biomonitoring study. Int J Environ Res Public Health 2017; 14(12): 1456-68.
[http://dx.doi.org/10.3390/ijerph14121456] [PMID: 29186834]
[30]
Rocha BA, Asimakopoulos AG, Barbosa F Jr, Kannan K. Urinary concentrations of 25 phthalate metabolites in Brazilian children and their association with oxidative DNA damage. Sci Total Environ 2017; 586: 152-62.
[http://dx.doi.org/10.1016/j.scitotenv.2017.01.193] [PMID: 28174045]
[31]
Dales RE, Kauri LM, Cakmak S. The associations between phthalate exposure and insulin resistance, β-cell function and blood glucose control in a population-based sample. Sci Total Environ 2018; 612: 1287-92.
[http://dx.doi.org/10.1016/j.scitotenv.2017.09.009] [PMID: 28898934]
[32]
Mengozzi A, Carli F, Biancalana E, et al. Phthalates exposure as determinant of albuminuria in subjects with type 2 diabetes: A cross-sectional study. J Clin Endocrinol Metab 2019; 104(5): 1491-9.
[http://dx.doi.org/10.1210/jc.2018-01797] [PMID: 30462244]
[33]
Shoshtari-Yeganeh B, Zarean M, Mansourian M, et al. Systematic review and meta-analysis on the association between phthalates exposure and insulin resistance. Environ Sci Pollut Res Int 2019; 26(10): 9435-42.
[http://dx.doi.org/10.1007/s11356-019-04373-1] [PMID: 30734259]
[34]
Lee HA, Park SH, Hong YS, Ha EH, Park H. The effect of exposure to persistent organic pollutants on metabolic health among Korean children during a 1-year follow-up. Int J Environ Res Public Health 2016; 13(3): 270-81.
[http://dx.doi.org/10.3390/ijerph13030270] [PMID: 26938545]
[35]
Gasull M, Bosch de Basea M, Puigdomènech E, Pumarega J, Porta M. Empirical analyses of the influence of diet on human concentrations of persistent organic pollutants: a systematic review of all studies conducted in Spain. Environ Int 2011; 37(7): 1226-35.
[http://dx.doi.org/10.1016/j.envint.2011.05.008] [PMID: 21683445]
[36]
Chang JW, Chen HL, Su HJ, Liao PC, Lee CC. Biochemical study of retired pentachlorophenol workers with and without following dietary exposure to PCDD/Fs. Chemosphere 2012; 88(7): 813-9.
[http://dx.doi.org/10.1016/j.chemosphere.2012.03.087] [PMID: 22579452]
[37]
Ruzzin J, Petersen R, Meugnier E, et al. Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 2010; 118(4): 465-71.
[http://dx.doi.org/10.1289/ehp.0901321] [PMID: 20064776]
[38]
Takuma M, Ushijima K, Kumazaki M, Ando H, Fujimura A. Influence of dioxin on the daily variation of insulin sensitivity in mice. Environ Toxicol Pharmacol 2015; 40(2): 349-51.
[http://dx.doi.org/10.1016/j.etap.2015.07.008] [PMID: 26233560]
[39]
Regnier SM, Kirkley AG, Ye H, et al. Dietary exposure to the endocrine disruptor tolylfluanid promotes global metabolic dysfunction in male mice. Endocrinology 2015; 156(3): 896-910.
[http://dx.doi.org/10.1210/en.2014-1668] [PMID: 25535829]
[40]
Burns JS, Williams PL, Korrick SA, et al. Association between chlorinated pesticides in the serum of prepubertal Russian boys and longitudinal biomarkers of metabolic function. Am J Epidemiol 2014; 180(9): 909-19.
[http://dx.doi.org/10.1093/aje/kwu212] [PMID: 25255811]
[41]
Park SH, Ha E, Hong YS, Park H. Serum levels of persistent organic pollutants and insulin secretion among children age 7-9 years: A prospective cohort study. Environ Health Perspect 2016; 124(12): 1924-30.
[http://dx.doi.org/10.1289/EHP147] [PMID: 27266903]
[42]
Lee DH, Steffes MW, Sjödin A, Jones RS, Needham LL, Jacobs DR Jr. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One 2011; 6(1): e15977.
[http://dx.doi.org/10.1371/journal.pone.0015977] [PMID: 21298090]
[43]
Suarez-Lopez JR, Lee DH, Porta M, Steffes MW, Jacobs DR Jr. Persistent organic pollutants in young adults and changes in glucose related metabolism over a 23-year follow-up. Environ Res 2015; 137: 485-94.
[http://dx.doi.org/10.1016/j.envres.2014.11.001] [PMID: 25706918]
[44]
Kim KS, Hong NS, Jacobs DR Jr, Lee DH. Interaction between persistent organic pollutants and C-reactive protein in estimating insulin resistance among non-diabetic adults. J Prev Med Public Health 2012; 45(2): 62-9.
[http://dx.doi.org/10.3961/jpmph.2012.45.2.62] [PMID: 22509446]
[45]
FÆRCH K. et al. Increased serum concentrations of persistent organic pollutants among prediabetic individuals: Potential role of altered substrate oxidation patterns. Clin Endocrinol Metab 2012; 97: 1705-13.
[http://dx.doi.org/10.1210/jc.2012-1342]
[46]
Pal S, Blais JM, Robidoux MA, et al. The association of type 2 diabetes and insulin resistance/secretion with persistent organic pollutants in two First Nations communities in northern Ontario. Diabetes Metab 2013; 39(6): 497-504.
[http://dx.doi.org/10.1016/j.diabet.2013.01.006] [PMID: 23639570]
[47]
Wu H, Bertrand KA, Choi AL, et al. WU H. et al. Persistent organic pollutants and type 2 diabetes: a prospective analysis in the nurses’ health study and meta-analysis. Environ Health Perspect 2013; 121(2): 153-61.
[http://dx.doi.org/10.1289/ehp.1205248] [PMID: 23131992]
[48]
Solomon GM, Schettler T. Environment and health: 6. Endocrine disruption and potential human health implications. CMAJ 2000; 163(11): 1471-6.
[PMID: 11192656]
[49]
Hatch EE, Nelson JW, Stahlhut RW, Webster TF. Association of endocrine disruptors and obesity: perspectives from epidemiological studies. Int J Androl 2010; 33(2): 324-32.
[http://dx.doi.org/10.1111/j.1365-2605.2009.01035.x] [PMID: 20113374]
[50]
Hayes TB. Welcome to the revolution: integrative biology and assessing the impact of endocrine disruptors on environmental and public health. Integr Comp Biol 2005; 45(2): 321-9.
[http://dx.doi.org/10.1093/icb/45.2.321] [PMID: 21676775]
[51]
Ormond G, Nieuwenhuijsen MJ, Nelson P, et al. Endocrine disruptors in the workplace, hair spray, folate supplementation, and risk of hypospadias: case-control study. Environ Health Perspect 2009; 117(2): 303-7.
[http://dx.doi.org/10.1289/ehp.11933] [PMID: 19270804]
[52]
DeRosa C, Richter P, Pohl H, Jones DE. Environmental exposures that affect the endocrine system: public health implications. J Toxicol Environ Health B Crit Rev 1998; 1(1): 3-26.
[http://dx.doi.org/10.1080/10937409809524541] [PMID: 9487091]
[53]
Legler J, Hamers T. The OBELIX project: early life exposure to endocrine disruptors and obesity. The American journal of clinical nutrition 2011; 94(suppl_6): 1933-8.
[54]
Birnbaum LS, Jung P. From endocrine disruptors to nanomaterials: advancing our understanding of environmental health to protect public health. Health Aff (Millwood) 2011; 30(5): 814-22.
[http://dx.doi.org/10.1377/hlthaff.2010.1225] [PMID: 21555467]
[55]
Janesick AS, Blumberg B. Obesogens: an emerging threat to public health. Am J Obstet Gynecol 2016; 214(5): 559-65.
[http://dx.doi.org/10.1016/j.ajog.2016.01.182] [PMID: 26829510]
[56]
Grabic R, Jurcikova J, Tomsejova S, et al. Passive sampling methods for monitoring endocrine disruptors in the Svratka and Svitava rivers in the Czech Republic. Environmental Toxicology and Chemistry: An International Journal 2010; 29(3): 550-5.
[http://dx.doi.org/10.1002/etc.85] [PMID: 20821477]
[57]
Guillette LJ Jr. Organochlorine pesticides as endocrine disruptors in wildlife. Cent Eur J Public Health 2000; 8(Suppl.): 34-5.
[PMID: 10943450]
[58]
Safe S. Endocrine disruptors and human health: is there a problem. Toxicology 2004; 205(1-2): 3-10.
[http://dx.doi.org/10.1016/j.tox.2004.06.032] [PMID: 15458784]
[59]
Monneret C. What is an endocrine disruptor? C R Biol 2017; 340(9-10): 403-5.
[http://dx.doi.org/10.1016/j.crvi.2017.07.004] [PMID: 29126512]
[60]
Cwiek-Ludwicka K, Ludwicki JK. Endocrine disruptors in food contact materials; is there a health threat? Rocz Panstw Zakl Hig 2014; 65(3): 169-77.
[PMID: 25247795]
[61]
De Coster S, van Larebeke N. Endocrine-disrupting chemicals: associated disorders and mechanisms of action. J Environ Public Health 2012; 2012: 713696.
[http://dx.doi.org/10.1155/2012/713696] [PMID: 22991565]
[62]
Elobeid MA, Allison DB. Putative environmental-endocrine disruptors and obesity: a review. Curr Opin Endocrinol Diabetes Obes 2008; 15(5): 403-8.
[http://dx.doi.org/10.1097/MED.0b013e32830ce95c] [PMID: 18769210]
[63]
Vogel JM. Tunnel vision: The regulation of endocrine disruptors. Policy Sci 2004; 37(3-4): 277-303.
[http://dx.doi.org/10.1007/s11077-005-1764-0]
[64]
Waissmann W. Health surveillance and endocrine disruptors. Cad Saude Publica 2002; 18(2): 511-7.
[http://dx.doi.org/10.1590/S0102-311X2002000200016] [PMID: 11923893]
[65]
Melnick R, Lucier G, Wolfe M, et al. Summary of the National Toxicology Program’s report of the endocrine disruptors low-dose peer review. Environ Health Perspect 2002; 110(4): 427-31.
[http://dx.doi.org/10.1289/ehp.02110427] [PMID: 11940462]
[66]
Birnbaum L S, Fenton S E. 2003; Cancer and developmental exposure to endocrine disruptors Environmental health perspectives 2003; 111(4): 389-94.
[http://dx.doi.org/10.1289/ehp.5686]
[67]
Engel SM, Wolff MS. Causal inference considerations for endocrine disruptor research in children’s health. Annu Rev Public Health 2013; 34: 139-58.
[http://dx.doi.org/10.1146/annurev-publhealth-031811-124556] [PMID: 23514318]
[68]
Mori Chisato. Possible effects of endocrine disruptors on male reproductive function. Kaibogaku zasshi. Journal of anatomy 2001; 76(4): 361.
[69]
Soto AM, Sonnenschein C. Environmental causes of cancer: endocrine disruptors as carcinogens. Nat Rev Endocrinol 2010; 6(7): 363-70.
[http://dx.doi.org/10.1038/nrendo.2010.87] [PMID: 20498677]
[70]
Heindel JJ. Endocrine disruptors and the obesity epidemic. Toxicol Sci 2003; 76(2): 247-9.
[http://dx.doi.org/10.1093/toxsci/kfg255] [PMID: 14677558]
[71]
Newbold RR, Padilla-Banks E, Jefferson WN, Heindel JJ. Effects of endocrine disruptors on obesity. Int J Androl 2008; 31(2): 201-8.
[http://dx.doi.org/10.1111/j.1365-2605.2007.00858.x] [PMID: 18315718]
[72]
Heindel JJ, Newbold R, Schug TT. Endocrine disruptors and obesity. Nat Rev Endocrinol 2015; 11(11): 653-61.
[http://dx.doi.org/10.1038/nrendo.2015.163] [PMID: 26391979]
[73]
Kelce WR, Gray LE, Wilson EM. Antiandrogens as environmental endocrine disruptors. Reprod Fertil Dev 1998; 10(1): 105-11.
[http://dx.doi.org/10.1071/R98051] [PMID: 9727600]
[74]
Birnbaum L S. State of the science of endocrine disruptors 2013.State of the science of endocrine disruptors
[http://dx.doi.org/10.1289/ehp.1306695]
[75]
Iavicoli I, Fontana L, Leso V, Bergamaschi A. The effects of nanomaterials as endocrine disruptors. Int J Mol Sci 2013; 14(8): 16732-801.
[http://dx.doi.org/10.3390/ijms140816732] [PMID: 23949635]
[76]
Petrakis D, Vassilopoulou L, Mamoulakis C, et al. Endocrine disruptors leading to obesity and related diseases. Int J Environ Res Public Health 2017; 14(10): 1282.
[http://dx.doi.org/10.3390/ijerph14101282] [PMID: 29064461]
[77]
de Cock M, de Boer MR, Lamoree M, Legler J, van de Bor M. First year growth in relation to prenatal exposure to endocrine disruptors - a Dutch prospective cohort study. Int J Environ Res Public Health 2014; 11(7): 7001-21.
[http://dx.doi.org/10.3390/ijerph110707001] [PMID: 25014249]
[78]
Newbold RR. Impact of environmental endocrine disrupting chemicals on the development of obesity. Hormones (Athens) 2010; 9(3): 206-17.
[http://dx.doi.org/10.14310/horm.2002.1271] [PMID: 20688618]
[79]
Todaka E, Mori C. Necessity to establish new risk assessment and risk communication for human fetal exposure to multiple endocrine disruptors in Japan. Congenit Anom (Kyoto) 2002; 42(2): 87-93.
[http://dx.doi.org/10.1111/j.1741-4520.2002.tb00857.x] [PMID: 12196705]
[80]
Nansheng L X B. Study Progress of Environmental Endocrine Disruptors [J]. Shanghai Environmental Sciences 2003; 1
[81]
Ma L. Endocrine disruptors in female reproductive tract development and carcinogenesis. Trends Endocrinol Metab 2009; 20(7): 357-63.
[http://dx.doi.org/10.1016/j.tem.2009.03.009] [PMID: 19709900]
[82]
Zoeller RT, Brown TR, Doan LL, et al. Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. Endocrinology 2012; 153(9): 4097-110.
[http://dx.doi.org/10.1210/en.2012-1422] [PMID: 22733974]
[83]
Meeker JD. Exposure to environmental endocrine disruptors and child development. Arch Pediatr Adolesc Med 2012; 166(10): 952-8.
[http://dx.doi.org/10.1001/archpediatrics.2012.241] [PMID: 23367522]
[84]
Laviola G, Gioiosa L, Adriani W, Palanza P. D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors. Brain Res Bull 2005; 65(3): 235-40.
[http://dx.doi.org/10.1016/j.brainresbull.2004.11.015] [PMID: 15811586]
[85]
Alonso-Magdalena P, Quesada I, Nadal A. Endocrine disruptors in the etiology of type 2 diabetes mellitus. Nat Rev Endocrinol 2011; 7(6): 346-53.
[http://dx.doi.org/10.1038/nrendo.2011.56] [PMID: 21467970]
[86]
Jackson W, Steingraber S. Protecting public health and the environment: implementing the precautionary principle.Island Press 1999.
[87]
Goldstein BD. The precautionary principle also applies to public health actions. Am J Public Health 2001; 91(9): 1358-61.
[http://dx.doi.org/10.2105/AJPH.91.9.1358] [PMID: 11527755]
[88]
Martuzzi M, Tickner J A. The precautionary principle: protecting public health, the environment and the future of our children. 2004.
[89]
Kriebel D, Tickner J. Reenergizing public health through precaution. Am J Public Health 2001; 91(9): 1351-5.
[http://dx.doi.org/10.2105/AJPH.91.9.1351] [PMID: 11527753]
[90]
Martuzzi M. The precautionary principle: in action for public health. 2007.
[http://dx.doi.org/10.1136/oem.2006.030601]
[91]
Chaudry RV. The Precautionary Principle, public health, and public health nursing. Public Health Nurs 2008; 25(3): 261-8.
[http://dx.doi.org/10.1111/j.1525-1446.2008.00703.x] [PMID: 18477377]
[92]
Goklany IM. From precautionary principle to risk-risk analysis. Nat Biotechnol 2002; 20(11): 1075-5.
[http://dx.doi.org/10.1038/nbt1102-1075] [PMID: 12410243]
[93]
Grandjean P. Implications of the precautionary principle for primary prevention and research. Annu Rev Public Health 2004; 25: 199-223.
[http://dx.doi.org/10.1146/annurev.publhealth.25.050503.153941] [PMID: 15015918]
[94]
Wiedemann PM, Schütz H. The precautionary principle and risk perception: experimental studies in the EMF area. Environ Health Perspect 2005; 113(4): 402-5.
[http://dx.doi.org/10.1289/ehp.7538] [PMID: 15811829]
[95]
Fisher EC, Jones JS, von Schomberg R. Implementing the precautionary principle: perspectives and prospects.Edward Elgar Publishing 2006.
[http://dx.doi.org/10.4337/9781847201676]
[96]
Ladeur KH. Introduction of the Precautionary Principle into EU Law: A Pyrrhic Victory for Environmental and Public Health Law-Decision-Making under Conditions of Complexity in Multi-Level Political Systems, The. Common Market L. Rev 2003; 40: 1455.
[97]
Charnley G, Elliott ED. Risk versus precaution: environmental law and public health protection. Envtl L Rep News & Analysis 2002; 32: 10363.
[98]
Thornton JW, McCally M, Houlihan J. Biomonitoring of industrial pollutants: health and policy implications of the chemical body burden. Public Health Rep 2002; 117(4): 315-23.
[http://dx.doi.org/10.1016/S0033-3549(04)50167-X] [PMID: 12477912]
[99]
Gilbertson M. The precautionary principle and early warnings of chemical contamination of the Great Lakes. Late lessons from early warnings: the precautionary principle 2001; 126: 1896-2000.
[100]
Winston G, Leventhal A. Unintentional drinking-water contamination events of unknown origin: surrogate for terrorism preparedness. J Water Health 2008; 6(S1)(Suppl. 1): 11-9.
[http://dx.doi.org/10.2166/wh.2008.036] [PMID: 18401124]
[101]
Brecher ME, Hay SN. Bacterial contamination of blood components. Clin Microbiol Rev 2005; 18(1): 195-204.
[http://dx.doi.org/10.1128/CMR.18.1.195-204.2005] [PMID: 15653826]
[102]
Phillips I. Withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health. Int J Antimicrob Agents 2007; 30(2): 101-7.
[http://dx.doi.org/10.1016/j.ijantimicag.2007.02.018] [PMID: 17467959]
[103]
Daughton CG. Non-regulated water contaminants: emerging research. Environ Impact Assess Rev 2004; 24(7-8): 711-32.
[http://dx.doi.org/10.1016/j.eiar.2004.06.003]
[104]
Kriebel D, Tickner J, Epstein P, et al. The precautionary principle in environmental science. Environ Health Perspect 2001; 109(9): 871-6.
[http://dx.doi.org/10.1289/ehp.01109871] [PMID: 11673114]
[105]
Houtman CJ. Emerging contaminants in surface waters and their relevance for the production of drinking water in Europe. J Integr Environ Sci 2010; 7(4): 271-95.
[http://dx.doi.org/10.1080/1943815X.2010.511648]
[106]
Cogan TA, Bloomfield SF, Humphrey TJ. The effectiveness of hygiene procedures for prevention of cross-contamination from chicken carcases in the domestic kitchen. Lett Appl Microbiol 1999; 29(5): 354-8.
[http://dx.doi.org/10.1046/j.1472-765X.1999.00656.x] [PMID: 10664978]
[107]
Goldstein BD, Carruth RS. Implications of the precautionary principle for environmental regulation in the United States: examples from the control of hazardous air pollutants in the 1990 Clean Air Act amendments. Law Contemp Probl 2003; 66: 247.
[108]
MacGarvin M. The implications of the precautionary principle for biological monitoring. Helgol Meeresunters 1995; 49(1): 647.
[http://dx.doi.org/10.1007/BF02368389]
[109]
Fisher EC, Jones JS, von Schomberg R. Implementing the precautionary principle: perspectives and prospects.Edward Elgar Publishing 2006.
[http://dx.doi.org/10.4337/9781847201676]
[110]
Maguire S, Ellis J. Redistributing the burden of scientific uncertainty: implications of the precautionary principle for state and nonstate actors. Glob Gov 2005; 11: 505.
[http://dx.doi.org/10.1163/19426720-01104007]
[111]
Goldstein BD, Carruth RS. Implications of the Precautionary Principle: is it a threat to science? Int J Occup Med Environ Health 2004; 17(1): 153-61.
[PMID: 15212219]
[112]
Cranor CF. Some legal implications of the Precautionary Principle: improving information-generation and legal protections. Hum Ecol Risk Assess 2005; 11(1): 29-52.
[http://dx.doi.org/10.1080/10807030590919873]
[113]
Weed DL. Methodologic implications of the Precautionary Principle: causal criteria. Int J Occup Med Environ Health 2004; 17(1): 77-81.
[PMID: 15212209]
[114]
Gee D, MacGarvin M, Stirling A, Keys J, Wynne B, Vaz SG. Late lessons from early warnings: the precautionary principle 1896-2000. P. Harremoës.Luxembourg: Office for Official Publications of the European Communities 2001.
[115]
Majone G. The precautionary principle and its policy implications. J Common Mark Stud 2002; 40(1): 89-109.
[http://dx.doi.org/10.1111/1468-5965.00345]
[116]
Von Schomberg R. The precautionary principle and its normative challenges. Implementing the precautionary principle: Perspectives and prospects 19-42. 2006; 19-42.
[http://dx.doi.org/10.4337/9781847201676.00011]
[117]
Tickner JA, Hoppin P. Children’s environmental health: a case study in implementing the precautionary principle. Int J Occup Environ Health 2000; 6(4): 281-8.
[http://dx.doi.org/10.1179/oeh.2000.6.4.281] [PMID: 11114121]
[118]
Guldberg H. Child protection and the precautionary principle. Rethinking Risk and the Precautionary Principal.Oxford, UK: Butterworth-Heinemann 2000; pp. 127-39.
[119]
Jarosinska D, Gee D. Children’s environmental health and the precautionary principle. Int J Hyg Environ Health 2007; 210(5): 541-6.
[http://dx.doi.org/10.1016/j.ijheh.2007.07.017] [PMID: 17889608]
[120]
Mayer B, Brown P, Linder M. Moving further upstream: from toxics reduction to the precautionary principle. Public Health Rep 2002; 117(6): 574-86.
[http://dx.doi.org/10.1016/S0033-3549(04)50202-9] [PMID: 12576537]
[121]
Resnik DB. The precautionary principle and medical decision making. J Med Philos 2004; 29(3): 281-99.
[http://dx.doi.org/10.1080/03605310490500509] [PMID: 15512973]
[122]
Hooper K, She J. Lessons from the polybrominated diphenyl ethers (PBDEs): precautionary principle, primary prevention, and the value of community-based body-burden monitoring using breast milk. Environ Health Perspect 2003; 111(1): 109-14.
[http://dx.doi.org/10.1289/ehp.5438] [PMID: 12515688]
[123]
Cross FB. Paradoxical perils of the precautionary principle. Wash Lee Law Rev 1996; 53: 851.
[124]
Weir E, Schabas R, Wilson K, Mackie C. A Canadian framework for applying the precautionary principle to public health issues. Can J Public Health 2010; 101(5): 396-8.
[http://dx.doi.org/10.1007/BF03404860] [PMID: 21214055]
[125]
Morello-Frosch R, Pastor M Jr, Sadd J. Integrating environmental justice and the precautionary principle in research and policy making: the case of ambient air toxics exposures and health risks among schoolchildren in Los Angeles. Ann Am Acad Pol Soc Sci 2002; 584(1): 47-68.
[http://dx.doi.org/10.1177/000271620258400104]
[126]
Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004; 291(23): 2847-50.
[http://dx.doi.org/10.1001/jama.291.23.2847] [PMID: 15199035]
[127]
Antunes A, Moreira P. [Prevalence of overweight and obesity in Portuguese children and adolescents]. Acta Med Port 2011; 24(2): 279-84.
[PMID: 22011600]
[128]
de Onis M, Blössner M, Borghi E. Global prevalence and trends of overweight and obesity among preschool children. Am J Clin Nutr 2010; 92(5): 1257-64.
[http://dx.doi.org/10.3945/ajcn.2010.29786] [PMID: 20861173]
[129]
Lamerz A, Kuepper-Nybelen J, Wehle C, et al. Social class, parental education, and obesity prevalence in a study of six-year-old children in Germany. Int J Obes 2005; 29(4): 373-80.
[http://dx.doi.org/10.1038/sj.ijo.0802914] [PMID: 15768043]
[130]
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012; 307(5): 483-90.
[http://dx.doi.org/10.1001/jama.2012.40] [PMID: 22253364]
[131]
Sinha R, Fisch G, Teague B, et al. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Engl J Med 2002; 346(11): 802-10.
[http://dx.doi.org/10.1056/NEJMoa012578] [PMID: 11893791]
[132]
CWIEK-LUDWICKA. Bisphenol A [BPA] in food contact materials-new scientific opinion from EFSA regarding public health risk. Roczniki Państwowego Zakładu Higieny 2015; 66(4)
[133]
Skelton JA, Cook SR, Auinger P, Klein JD, Barlow S E, et al. US FOOD AND DRUG ADMINISTRATION. Prevalence and trends of severe obesity among US children and adolescents. Academic pediatrics 2014; 9(5): 322-9.
[134]
Walter J. The CDC Fourth National Report on Human Exposure to Environmental Chemicals: What it Tells Us About our Toxic Burden and How it Assists Environmental Medicine Physicians. Altern Med Rev 2010; 15.
[135]
STOKKE. Stockholm Convention Persistent Organic Pollutants [Stockholm Convention: POPs].In: Yearbook of International Cooperation on Environment and Development. Routledge 2013; pp. 122-3.
[136]
Shirin A, RAHMAN ABDEL, Wael M. HAFEZI. The endocrine disruptor bisphenol A [BPA] exerts a wide range of effects in carcinogenesis and response to therapy. Current molecular pharmacology 2019; 12(3): 230-8.
[137]
ZOELLER. The Endocrine Society in Endocrine Disruptor Research and Policy. Endocrinology 2019; 160.
[138]
Caballero B. Obesity prevention in children: opportunities and challenges. Int J Obes 2004; 28(3)(Suppl. 3): S90-5.
[http://dx.doi.org/10.1038/sj.ijo.0802797] [PMID: 15543227]
[139]
FERENHOF H. A. FERNANDES R. F. Desmistificando a revisão de literatura como base para redação científica: Métodos SSF. Revista ACB 2016; 21: 550-63.
[140]
Neel BA, Sargis RM. The paradox of progress: environmental disruption of metabolism and the diabetes epidemic. Diabetes 2011; 60(7): 1838-48.
[http://dx.doi.org/10.2337/db11-0153] [PMID: 21709279]
[141]
Verstraete S, Vanhorebeek I, Covaci A, et al. Circulating phthalates during critical illness in children are associated with long-term attention deficit: a study of a development and a validation cohort. Intensive Care Med 2016; 42(3): 379-92.
[http://dx.doi.org/10.1007/s00134-015-4159-5] [PMID: 26667027]
[142]
Li G, Chang H, Xia W, Mao Z, Li Y, Xu S. LI G. et al. F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck. Toxicol Lett 2014; 228(3): 192-9.
[http://dx.doi.org/10.1016/j.toxlet.2014.04.012] [PMID: 24793715]
[143]
Rajesh P, Balasubramanian K. Gestational exposure to di(2-ethylhexyl) phthalate (DEHP) impairs pancreatic β-cell function in F1 rat offspring. Toxicol Lett 2015; 232(1): 46-57.
[http://dx.doi.org/10.1016/j.toxlet.2014.09.025] [PMID: 25280772]
[144]
Nadal A. Obesity: Fat from plastics? Linking bisphenol A exposure and obesity. Nat Rev Endocrinol 2013; 9(1): 9-10.
[http://dx.doi.org/10.1038/nrendo.2012.205] [PMID: 23147575]
[145]
Marjorie E, et al. BATEMAN. The effects of endocrine disruptors on adipogenesis and osteogenesis in mesenchymal stem cells: a review. Frontiers in endocrinology 2017; 7: 171.
[146]
Foulds CE, Treviño LS, York B, Walker CL. Endocrine-disrupting chemicals and fatty liver disease. Nat Rev Endocrinol 2017; 13(8): 445-57.
[http://dx.doi.org/10.1038/nrendo.2017.42] [PMID: 28524171]
[147]
Wei J, Sun X, Chen Y, et al. Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet. J Endocrinol 2014; 222(3): 313-25.
[http://dx.doi.org/10.1530/JOE-14-0356] [PMID: 25112833]
[148]
CAPOROSSI L. PAPALEO B. Bisphenol A and metabolic diseases: Challenges for occupational medicine. Int J Environ Res Public Health 2017; 14: 959-73.
[http://dx.doi.org/10.3390/ijerph14090959]
[149]
BOMBARDI L M. Geografia do uso de agrotóxicos no Brasil e conexões com a União Europeia. 2017.
[150]
Attina TM, Hauser R, Sathyanarayana S, et al. Exposure to endocrine-disrupting chemicals in the USA: a population-based disease burden and cost analysis. Lancet Diabetes Endocrinol 2016; 4(12): 996-1003.
[http://dx.doi.org/10.1016/S2213-8587(16)30275-3] [PMID: 27765541]
[151]
Trasande L, Zoeller RT, Hass U, et al. Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European union. J Clin Endocrinol Metab 2015; 100(4): 1245-55.
[http://dx.doi.org/10.1210/jc.2014-4324] [PMID: 25742516]
[152]
Biemann R, Fischer B, Navarrete Santos A. Adipogenic effects of a combination of the endocrine-disrupting compounds bisphenol A, diethylhexylphthalate, and tributyltin. Obes Facts 2014; 7(1): 48-56.
[http://dx.doi.org/10.1159/000358913] [PMID: 24503497]

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