A Case of Quinacrine-induced Psychosis: Case Report

Title:A Case of Quinacrine-induced Psychosis: Case Report

Volume: 16 Issue: 3

Author(s): Anangamanjari Pedapudi*, Jonathan Stewart and Ankita Patel

Affiliation:

• Department of Psychiatry and Behavioral Neurosciences, University of South Florida Morsani College of Medicine, Tampa, FL33612,United States

Keywords: Quinacrine, quinolines, psychosis, adverse drug reaction, case report, giardiasis.

Abstract:

Background: Quinacrine is an older antimalarial drug that remains in use for a variety of illnesses including treatment-resistant giardiasis.

Case Presentation: We report a patient with no prior psychiatric history who developed mild, prodromal psychiatric symptoms when treated with quinacrine for treatment-resistant giardiasis. Symptoms resolved when the drug was stopped, recurred with greater severity (requiring involuntary psychiatric hospitalization) when restarted and promptly resolved again when the drug was finally stopped.

Conclusion: Although quinacrine remains in use today, providers may be unaware of its potential for serious neuropsychiatric toxicity.

Cite this article as:

Pedapudi Anangamanjari *, Stewart Jonathan and Patel Ankita , A Case of Quinacrine-induced Psychosis: Case Report, Current Drug Safety 2021; 16 (3) . https://dx.doi.org/10.2174/1574886315666201005103142