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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Editorial

Telomere Based Approach for Cancer Therapy

Author(s): Diego Madureira de Oliveira

Volume 20, Issue 6, 2020

Page: [409 - 409] Pages: 1

DOI: 10.2174/156802662006200305112748

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[1]
Sugarman, E.T.; Zhang, G.; Shay, J.W. In perspective: An update on telomere targeting in cancer. Mol. Carcinog., 2019, 58(9), 1581-1588.
[2]
Hoffman, H.; Skordalakes, E. Crystallographic studies of telomerase. Methods Enzymol., 2016, 573, 403-419.
[3]
Nguyen, T.H.D.; Tam, J.; Wu, R.A.; Greber, B.J.; Toso, D.; Nogales, E.; Collins, K. Cryo-EM structure of substrate-bound human telomerase holoenzyme. Nature, 2018, 557, 190-195.
[4]
Jiang, J.; Wang, Y.; Sušac, L.; Chan, H.; Basu, R.; Zhou, Z.H.; Feigon, J. Structure of telomerase with telomeric DNA. Cell, 2018, 173(5), 1179-1190.
[5]
Chen, X.; Tang, W.J.; Shi, J.B.; Liu, M.M.; Liu, X.H. Therapeutic strategies for targeting telomerase in cancer. Med. Res. Rev., 2019.
[http://dx.doi.org/10.1002/med.21626]
[6]
Bryan, C.; Rice, C.; Hoffman, H.; Harkisheimer, M.; Sweeney, M.; Skordalakes, E. Structural basis of telomerase inhibition by the highly specific BIBR1532. Structure, 2015, 23(10), 1934-1942.
[7]
Zhao, S.; Wang, F.; Liu, L. Alternative lengthening of telomeres (ALT) in tumors and pluripotent stem cells. Genes (Basel), 2019, 10(12). PII: E1030.
[8]
Sugarman, E.T.; Zhang, G.; Shay, J.W. In perspective: An update on telomere targeting in cancer. Mol. Carcinog., 2019, 58(9), 1581-1588.
[9]
Ségal-Bendirdjian, E.; Geli, V. Non-canonical roles of telomerase: unraveling the imbroglio. Front. Cell Dev. Biol., 2019, 10(7), 332.

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