Abstract
As multi-component reactions have been among the most important and advantageous methodologies in organic chemistry since 150 years ago, the present review focuses on one-pot multi-component reactions containing amines and carbon disulfide as constant starting materials along with other essential substances to afford the corresponding nitrogen- and sulfur-containing products in demand such as thiazolidine-2-thiones, 2- imino-1,3-dithiolanes, 2-substituted benzothiazoles, 1,3-thiazine-2-thiones, dithiocarbamate derivatives, and thioureas through green methodologies. This synthetic field has been widely studied throughout the last two decades to achieve such biologically active structures. The progress orientation of these reports towards green chemistry principles is reviewed from 2000 to December 2017.
Keywords: Carbon disulfide, amines, multicomponent reactions, green synthesis, heteroatom containing compound, green chemistry.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
47
7
1