Abstract
Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.
Keywords: Sesterterpenes, scalaranes, linear sesterterpenes norsesterterpenes, biological activity, cytotoxic, antiproliferative, natural products discovery.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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