Abstract
As multi-component reactions have been among the most important and advantageous methodologies in organic chemistry since 150 years ago, the present review focuses on one-pot multi-component reactions containing amines and carbon disulfide as constant starting materials along with other essential substances to afford the corresponding nitrogen- and sulfur-containing products in demand such as thiazolidine-2-thiones, 2- imino-1,3-dithiolanes, 2-substituted benzothiazoles, 1,3-thiazine-2-thiones, dithiocarbamate derivatives, and thioureas through green methodologies. This synthetic field has been widely studied throughout the last two decades to achieve such biologically active structures. The progress orientation of these reports towards green chemistry principles is reviewed from 2000 to December 2017.
Keywords: Carbon disulfide, amines, multicomponent reactions, green synthesis, heteroatom containing compound, green chemistry.
Graphical Abstract
Current Organic Chemistry
Title:Utilizing Amines and Carbon Disulfide to Obtain Nitrogen- and Sulfur-containing Compounds under Green Conditions: A Review
Volume: 22 Issue: 24
Author(s): Maryam Fardpour, Arefeh Shafie, Saeed Bahadorikhalili, Bagher Larijani and Mohammad Mahdavi*
Affiliation:
- Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran,Iran
Keywords: Carbon disulfide, amines, multicomponent reactions, green synthesis, heteroatom containing compound, green chemistry.
Abstract: As multi-component reactions have been among the most important and advantageous methodologies in organic chemistry since 150 years ago, the present review focuses on one-pot multi-component reactions containing amines and carbon disulfide as constant starting materials along with other essential substances to afford the corresponding nitrogen- and sulfur-containing products in demand such as thiazolidine-2-thiones, 2- imino-1,3-dithiolanes, 2-substituted benzothiazoles, 1,3-thiazine-2-thiones, dithiocarbamate derivatives, and thioureas through green methodologies. This synthetic field has been widely studied throughout the last two decades to achieve such biologically active structures. The progress orientation of these reports towards green chemistry principles is reviewed from 2000 to December 2017.
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Cite this article as:
Fardpour Maryam , Shafie Arefeh, Bahadorikhalili Saeed , Larijani Bagher and Mahdavi Mohammad *, Utilizing Amines and Carbon Disulfide to Obtain Nitrogen- and Sulfur-containing Compounds under Green Conditions: A Review, Current Organic Chemistry 2018; 22 (24) . https://dx.doi.org/10.2174/1385272822666181029113222
DOI https://dx.doi.org/10.2174/1385272822666181029113222 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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