Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) is a widespread diagnosis that affects many children and adolescents’ ability to function and succeed in academics, socially, or other situations. Non-stimulant medications have become widely utilized in this population, especially in stimulant-resistant individuals, whether due to poor efficacy or intolerance of side effects. However, these, too, harbor their own side effect profiles, including cardiovascular and sleep or energy level disturbances.
Objectives: We review the literature in discussion of the presentation and management of these adverse events for non-stimulant medications for ADHD, with a particular focus on atomoxetine and alpha agonists guanfacine and clonidine.
Conclusion: Non-stimulants are for the most part well tolerated but monitoring for cardiac and sleep difficulty is warranted.
Keywords: Mental health, children and adolescents, psychopharmacology, ADHD, attention deficit disorder, atomoxetine, alpha agonists.
Graphical Abstract
Current Psychopharmacology
Title:Adverse Effects of Non-Stimulant ADHD Drugs: Atomoxetine, Alpha-Agonists
Volume: 7
Author(s): Myrtha Gregoire-Bottex*Katherine Soe
Affiliation:
- Department of Pediatrics and Adolescent Medicine, Western Michigan University, Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, Michigan, MI,United States
Keywords: Mental health, children and adolescents, psychopharmacology, ADHD, attention deficit disorder, atomoxetine, alpha agonists.
Abstract: Background: Attention-deficit/hyperactivity disorder (ADHD) is a widespread diagnosis that affects many children and adolescents’ ability to function and succeed in academics, socially, or other situations. Non-stimulant medications have become widely utilized in this population, especially in stimulant-resistant individuals, whether due to poor efficacy or intolerance of side effects. However, these, too, harbor their own side effect profiles, including cardiovascular and sleep or energy level disturbances.
Objectives: We review the literature in discussion of the presentation and management of these adverse events for non-stimulant medications for ADHD, with a particular focus on atomoxetine and alpha agonists guanfacine and clonidine.
Conclusion: Non-stimulants are for the most part well tolerated but monitoring for cardiac and sleep difficulty is warranted.
Export Options
About this article
Cite this article as:
Gregoire-Bottex Myrtha *, Soe Katherine , Adverse Effects of Non-Stimulant ADHD Drugs: Atomoxetine, Alpha-Agonists, Current Psychopharmacology 2018; 7 (1) . https://dx.doi.org/10.2174/2211556007666180328150248
DOI https://dx.doi.org/10.2174/2211556007666180328150248 |
Print ISSN 2211-5560 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5579 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Extrasynaptic GABA<sub>A</sub> Receptors in the Brainstem and Spinal Cord: Structure and Function
Current Pharmaceutical Design Molecular Basis of Mineralocorticoid Receptor Action in the Nervous System
CNS & Neurological Disorders - Drug Targets Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review
Mini-Reviews in Medicinal Chemistry Attitudes of Infertile Couples to a Multiple Birth: A Review of theLiterature and Results from a Survey
Current Women`s Health Reviews MicroRNA-542-3p Regulates P-glycoprotein Expression in Rat Epilepsy via the Toll-like Receptor 4/Nuclear Factor-kappaB Signaling Pathway
Current Neurovascular Research Transgenic Mouse Studies Reveal Substantial Roles for Opioid Receptors in the Rewarding Effects of Several Classes of Addictive Drugs
Current Psychiatry Reviews Alterations of Brain Membranes in Schizophrenia: Impact of Phospholipase A2
Current Topics in Medicinal Chemistry Influence of Propionate on Appetite Control and Metabolism
Current Nutrition & Food Science In Silico Design, Synthesis of Hybrid Combinations: Quercetin Based MAO Inhibitors with Antioxidant Potential
Current Topics in Medicinal Chemistry Current Research on How Infertility Affects the Sexuality of Men and Women
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) Editorial (Thematic Issue: Disorders of Consciousness: Recent Advances in Neurobiology and Treatments)
Current Pharmaceutical Design Receptors and Enzymes for Medical Sensing of L-Glutamate
Mini-Reviews in Medicinal Chemistry Cortical and Subcortical Changes in Alzheimer’s Disease: A Longitudinal and Quantitative MRI Study
Current Alzheimer Research The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamics
Current Pharmaceutical Design P2X7 Receptors: Channels, Pores and More
CNS & Neurological Disorders - Drug Targets Pharmacologic Treatment of Restless Legs Syndrome
Current Neuropharmacology Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer’s Disease
Current Neuropharmacology Hypertension and Compliance to Treatment in the Primary Care Setting: Key Issues from the Literature Review
Current Hypertension Reviews IL28B Polymorphism, Blood Interferon-Alpha Concentration, and Disease Stage of HCV Mono-Infected and HCV-HIV Co-Infected Patients
Current HIV Research Two Experts, One Goal: Collaborative Deprescribing in Psychiatry
Current Psychiatry Reviews