Abstract
Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Graphical Abstract
Current Organic Chemistry
Title:Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis
Volume: 22 Issue: 10
Author(s): Sandra Babic*, Martina Biosic and Irena Skoric
Affiliation:
- Department of Analytical Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, Zagreb,Croatia
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Abstract: Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
Export Options
About this article
Cite this article as:
Babic Sandra *, Biosic Martina and Skoric Irena , Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis, Current Organic Chemistry 2018; 22 (10) . https://dx.doi.org/10.2174/1385272822666171122160926
DOI https://dx.doi.org/10.2174/1385272822666171122160926 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Anti-Inflammatory/Analgesic
Current Bioactive Compounds Immunomodulatory Drugs: Immune Checkpoint Agents in Acute Leukemia
Current Drug Targets Identification of Novel IRAK-4 Inhibitors Through Pharmacophore Modeling, Atom-based 3D-QSAR, Docking Strategies and Molecular Dynamics Simulation
Letters in Drug Design & Discovery Possible Impact of Microglial Cells and the Monocyte-Macrophage System on Suicidal Behavior
CNS & Neurological Disorders - Drug Targets The Relationship Between Dietary Lipids and Serum Visfatin and Adiponectin Levels in Postmenopausal Women
Endocrine, Metabolic & Immune Disorders - Drug Targets Activation of Latent HIV-1 Expression by Protein Kinase C Agonists. A Novel Therapeutic Approach to Eradicate HIV-1 Reservoirs
Current Drug Targets Role of the Gut Microbiota in Age-Related Chronic Inflammation
Endocrine, Metabolic & Immune Disorders - Drug Targets Medullary Thyroid Cancer: A Promising Model for Targeted Therapy
Current Molecular Medicine Molecular Mechanisms Mediating Nociceptin/Orphanin FQ Receptor Signaling, Desensitization and Internalization
Current Molecular Pharmacology Editorial [Hot Topic: New Developments in Drug and Vaccine Discoveries (Executive Editor: Aldar S. Bourinbaiar)]
Current Pharmaceutical Design Vascular and Cellular Calcium in Normal and Hypertensive Pregnancy
Current Clinical Pharmacology Calcium Homeostasis Following Traumatic Neuronal Injury
Current Neurovascular Research Graphical Abstracts:
Current Angiogenesis (Discontinued) Novel Indications for Benzodiazepine Antagonist Flumazenil in GABA Mediated Pathological Conditions of the Central Nervous System
Current Pharmaceutical Design Poly(lactide-co-glycolide)-based Micro and Nanoparticles for the Controlled Drug Delivery of Vitamins
Current Nanoscience Approaches to Improve Efficiency of Dendritic Cell-based Therapy of High Grade Gliomas
Current Pharmaceutical Design The Analysis of Microorganisms by Microcalorimetry in the Pharmaceutical Industry
Current Pharmaceutical Biotechnology Targeting Aberrant TGF-β Signaling in Pre-Clinical Models of Cancer
Anti-Cancer Agents in Medicinal Chemistry Chemokines and Persistent Inflammation in Rheumatoid Arthritis: Hunting for Therapeutic Targets
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Microvesicles-mediated Cell Communication in Pulmonary Arterial Hypertension
Current Medicinal Chemistry