Natural Products as a Source of Antiarrhythmic Drugs

Title:Natural Products as a Source of Antiarrhythmic Drugs

Volume: 18 Issue: 4

Author(s): Arkadiy O. Bryzgalov*, Tatjana G. Tolstikova, Elvira E. Shults and Kristina O. Petrova

Affiliation:

• Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Prosp. Akad. Lavrentyeva, Novosibirsk 630090,Russian Federation

Keywords: Antiarrhythmic drugs, cardiovascular, chemical modifications, ischemic heart disease, plant substances, thyreoidea.

Abstract: Throughout the development of medicine, the spotlight has been held by the search for new drugs blocking different types of arrhythmia. In the past decade, much attention was given to the selection of active antiarrhythmic substances from plant material. It has been shown that these compounds have a good antiarrhythmic effect, and their chemical modifications substantially increase their major effects while adding other beneficial pharmacological properties. In this regard, work on the chemical modification of plant-source antiarrhythmics is highly relevant to the development of new and promising drugs.

Cite this article as:

Bryzgalov O. Arkadiy*, Tolstikova G. Tatjana, Shults E. Elvira and Petrova O. Kristina, Natural Products as a Source of Antiarrhythmic Drugs, Mini-Reviews in Medicinal Chemistry 2018; 18 (4) . https://dx.doi.org/10.2174/1389557516666161104144815