Abstract
Rhaponticin (RHA) is a stilbene glucoside compound that can be found in medicinal plant of Rheum L. RHA has been reported to possess several biological effects including antitumor, antithrombotic, antioxidant, vasorelaxant, defense for gastritis activities. It also shows beneficial activities on diabetic mice. According to reported literatures, an overview of spectroscopy characteristics, pharmacological activity, content determination and pharmacokinetics, etc. for RHA has been presented. Moreover, this work provides a certain reference value for developing the therapeutic drug of RHA.
Keywords: Rhaponticin, stilbene glucoside, anti-diabetic activity, structural characteristics of RHA, anti-oxidation activity, anti-allergic activity.
Graphical Abstract
Mini-Reviews in Organic Chemistry
Title:Review of Characteristics, Pharmacology, Determination and Pharmacokinetics of Rhaponticin
Volume: 14 Issue: 1
Author(s): Yang Sun, Xuhua Liang, Hua Cheng, Wanqiang Wang, Xiangsheng Jiang, Ping He, Yingyong Zhao and Junjun Wu
Affiliation:
Keywords: Rhaponticin, stilbene glucoside, anti-diabetic activity, structural characteristics of RHA, anti-oxidation activity, anti-allergic activity.
Abstract: Rhaponticin (RHA) is a stilbene glucoside compound that can be found in medicinal plant of Rheum L. RHA has been reported to possess several biological effects including antitumor, antithrombotic, antioxidant, vasorelaxant, defense for gastritis activities. It also shows beneficial activities on diabetic mice. According to reported literatures, an overview of spectroscopy characteristics, pharmacological activity, content determination and pharmacokinetics, etc. for RHA has been presented. Moreover, this work provides a certain reference value for developing the therapeutic drug of RHA.
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Cite this article as:
Sun Yang, Liang Xuhua, Cheng Hua, Wang Wanqiang, Jiang Xiangsheng, He Ping, Zhao Yingyong and Wu Junjun, Review of Characteristics, Pharmacology, Determination and Pharmacokinetics of Rhaponticin, Mini-Reviews in Organic Chemistry 2017; 14 (1) . https://dx.doi.org/10.2174/1570193X13666161102152403
DOI https://dx.doi.org/10.2174/1570193X13666161102152403 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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