Abstract
Type 2 Diabetes Mellitus (T2DM) and its complications are more prevalent in the elderly. As the general population worldwide is ageing, effective and safe treatment of older T2DM patients is becoming more important in clinical practice. Elderly T2DM patients should be carefully evaluated for functional, mental, geriatric and medical disorders before the initiation of antidiabetic drug therapy and regularly monitored thereafter. Treatment strategy and goals should be individualized based on patient comorbidities and drug pharmacokinetic and pharmacodynamic properties. This narrative review discusses the use of antidiabetic drugs in the elderly T2DM population.
Keywords: Elderly, type 2 diabetes mellitus, antidiabetic drugs, kidney dysfunction, diabetic complications.
Graphical Abstract
Current Vascular Pharmacology
Title:Type 2 Diabetes Mellitus and the Elderly: An Update on Drugs Used to Treat Glycaemia
Volume: 15 Issue: 1
Author(s): Asimina Mitrakou, Niki Katsiki and Nebojsa M. Lalic
Affiliation:
Keywords: Elderly, type 2 diabetes mellitus, antidiabetic drugs, kidney dysfunction, diabetic complications.
Abstract: Type 2 Diabetes Mellitus (T2DM) and its complications are more prevalent in the elderly. As the general population worldwide is ageing, effective and safe treatment of older T2DM patients is becoming more important in clinical practice. Elderly T2DM patients should be carefully evaluated for functional, mental, geriatric and medical disorders before the initiation of antidiabetic drug therapy and regularly monitored thereafter. Treatment strategy and goals should be individualized based on patient comorbidities and drug pharmacokinetic and pharmacodynamic properties. This narrative review discusses the use of antidiabetic drugs in the elderly T2DM population.
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Cite this article as:
Mitrakou Asimina, Katsiki Niki and Lalic M. Nebojsa, Type 2 Diabetes Mellitus and the Elderly: An Update on Drugs Used to Treat Glycaemia, Current Vascular Pharmacology 2017; 15 (1) . https://dx.doi.org/10.2174/1570161114666160822154816
DOI https://dx.doi.org/10.2174/1570161114666160822154816 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
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