Abstract
Background: Salvia species are used traditionally for treatment of many disorders all around the world. Salvia santolinifolia is a medicinal plant, traditionally used for treatment of inflammation, hypercholesterolemia, hemorrhoids and diarrhea.
Methods: In this study, antibacterial, antioxidant, toxicity, acetylcholinesterase and - glucosidase inhibitory activities of several extracts of S. santolinifolia were evaluated. Total phenol and flavonoid contents of the extracts were also determined.
Results: The MeOH extract showed high antioxidant activity in DPPH scavenging and ferric reducing power assays. All samples exhibited high acetylcholinesterase (IC50 = 42-89 g/ml) and -glucosidase inhibitory activities (IC50 = 24-174 g/ml). The MeOH extract showed great antibacterial and antifungal activities especially against Bacillus cereus and Candida albicans with MIC values from 10 to 200 g/ml.
Conclusion: Our findings indicated that S. santolinifolia is a rich source of natural compounds with strong antimicrobial, antidiabetic and anti-Alzheimer activities. This plant has great potential for several applications as pharmaceuticals and functional foods.
Keywords: Salvia, diabetes mellitus, alzheimer, antioxidant, antimicrobial, phenolic compounds.
Graphical Abstract
Current Bioactive Compounds
Title:Biological Activities of Salvia santolinifolia Boiss. A Multifunctional Medicinal Plant
Volume: 12 Issue: 4
Author(s): Mir Babak Bahadori, Hassan Valizadeh, Behvar Asghari, Leila Dinparast, Shahram Bahadori and Mahdi Moridi Farimani
Affiliation:
Keywords: Salvia, diabetes mellitus, alzheimer, antioxidant, antimicrobial, phenolic compounds.
Abstract: Background: Salvia species are used traditionally for treatment of many disorders all around the world. Salvia santolinifolia is a medicinal plant, traditionally used for treatment of inflammation, hypercholesterolemia, hemorrhoids and diarrhea.
Methods: In this study, antibacterial, antioxidant, toxicity, acetylcholinesterase and - glucosidase inhibitory activities of several extracts of S. santolinifolia were evaluated. Total phenol and flavonoid contents of the extracts were also determined.
Results: The MeOH extract showed high antioxidant activity in DPPH scavenging and ferric reducing power assays. All samples exhibited high acetylcholinesterase (IC50 = 42-89 g/ml) and -glucosidase inhibitory activities (IC50 = 24-174 g/ml). The MeOH extract showed great antibacterial and antifungal activities especially against Bacillus cereus and Candida albicans with MIC values from 10 to 200 g/ml.
Conclusion: Our findings indicated that S. santolinifolia is a rich source of natural compounds with strong antimicrobial, antidiabetic and anti-Alzheimer activities. This plant has great potential for several applications as pharmaceuticals and functional foods.
Export Options
About this article
Cite this article as:
Bahadori Mir Babak, Valizadeh Hassan, Asghari Behvar, Dinparast Leila, Bahadori Shahram and Farimani Moridi Mahdi, Biological Activities of Salvia santolinifolia Boiss. A Multifunctional Medicinal Plant, Current Bioactive Compounds 2016; 12 (4) . https://dx.doi.org/10.2174/1573407212666160426161112
DOI https://dx.doi.org/10.2174/1573407212666160426161112 |
Print ISSN 1573-4072 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6646 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Phytochemistry and Pharmacology of <i>Callistemon viminalis</i> (Myrtaceae): A Review
The Natural Products Journal Antiproliferative Activity of <i>Cissus quadrangularis</i> L. Extract Against Human Cervical Cancer Cells: In Vitro and In Silico Analysis
Anti-Cancer Agents in Medicinal Chemistry Anatomy, Physiology and Pathophysiology of Haemorrhoids
Reviews on Recent Clinical Trials Jatropha Curcas L., A Multipurpose Stress Resistant Plant with a Potential for Ethnomedicine and Renewable Energy
Current Pharmaceutical Biotechnology Antimicrobial, Gastroprotective and Healing Effect of the Hydroalcoholic Extract of Astronium fraxinifolium
Letters in Drug Design & Discovery Extraction and Evaluation of Anti-inflammatory and Analgesic Activity of Mimosa rubicaulis in Swiss Albino Rats
Anti-Infective Agents Recent Research on Flavonoids and their Biomedical Applications
Current Medicinal Chemistry Phytochemicals to Prevent Inflammation and Allergy
Recent Patents on Inflammation & Allergy Drug Discovery MicroRNAs in Prostate Cancer Following Radiotherapy: Towards Predicting Response to Radiation Treatment
Current Medicinal Chemistry Classifications and Clinical Assessment of Haemorrhoids: The Proctologist’s Corner
Reviews on Recent Clinical Trials Investigation of Antioxidant Activity and Analysis of Phenolic Compounds of some Asteraceae Plants by HPLC: A Comparison Between Methanol and Ethanol Extracts
Current Nutraceuticals Mucoadhesive Polymers for Delivery of Drugs to the Oral Cavity
Recent Patents on Drug Delivery & Formulation Cardioprotective Effects of Indian Gooseberry (Emblica officinalis Gaertn) and its Phytochemicals: A Review
Current Nutrition & Food Science The Clinical Impact of Quantitative Cell-free DNA, KRAS, and BRAF Mutations on Response to Anti-EGFR Treatment in Patients with Metastatic Colorectal Cancer
Current Pharmaceutical Design Prescription Patterns and Compliance with Antimicrobial Stewardship Team Recommendations Among Physicians in a Private Hospital in United Arab Emirates
New Emirates Medical Journal Recent Patents on Stimuli Responsive Hydrogel Drug Delivery System
Recent Patents on Drug Delivery & Formulation Safety and Efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A Prospective Randomized Clinical Trial
Reviews on Recent Clinical Trials A Case of Hepatotoxicity Induced by Adulterated “Tiger King”, a Chinese Herbal Medicine Containing Sildenafil
Current Drug Safety Alkannins and Shikonins: A New Class of Wound Healing Agents
Current Medicinal Chemistry Therapeutic Biology of Jatropha curcas: A Mini Review
Current Pharmaceutical Biotechnology