Generic placeholder image

Reviews on Recent Clinical Trials

Editor-in-Chief

ISSN (Print): 1574-8871
ISSN (Online): 1876-1038

Review Article

The Management of Hemorrhoidal Disease by Dearterialization and Mucopexy

Author(s): Veronica De Simone, Francesco Litta*, Angelo Parello, Paola Campennì, Raffaele Orefice, Angelo Alessandro Marra, Marta Goglia and Carlo Ratto

Volume 16, Issue 1, 2021

Published on: 06 May, 2020

Page: [60 - 66] Pages: 7

DOI: 10.2174/1574887115666200506091306

Abstract

Several minimally invasive surgical procedures have been recently developed to treat hemorrhoids without any excision. About 25 years ago, a non-excisional procedure providing doppler- guided ligation of the hemorrhoidal arteries has been proposed - named “hemorrhoidal dearterialization”. The original technique has been modified over the years, and indications were expanded. In particular, a plication of the redundant and prolapsing mucosa/submucosa of the rectum (named “mucopexy”) has been introduced to treat hemorrhoidal prolapse, without excision of the hemorrhoidal piles. At present, the THD® Doppler procedure is one of the most used techniques to treat hemorrhoids. Aim of this technique is to realize a target dearterialization, using a Doppler probe with the final purpose to reduce the arterial overflow to the hemorrhoidal piles. In the case of associated hemorrhoidal prolapse, a mucopexy is performed together with Doppler-guided dearterialization. The entity and circumferential extension of the hemorrhoidal prolapse guide the mucopexy, which can be considered tailored to a single patient; the dearterialization should be considered mandatory. Advantages of this surgical technique are the absence of serious and life-threatening postoperative events, chronic complications, and limited recurrence risks. The impact of the procedure on the anorectal physiology is negligible. However, careful postoperative management is mandatory to avoid complications and to guarantee an improved long-term outcome. Therefore, regular physiologic bowel movements, excessive strain at the defecation and strong physical activity are advisable.

Keywords: Hemorrhoids, dearterialization, mucopexy, doppler, THD, surgery.

Graphical Abstract

[1]
Gallo G, Sacco R, Sammarco G. Epidemiology of Hemorrhoidal Disease. Hemorrhoids Coloproctology. Cham: Springer 2018.
[2]
Burch J, Epstein D, Sari AB, et al. Stapled haemorrhoidopexy for the treatment of haemorrhoids: A systematic review. Colorectal Dis 2009; 11(3): 233-43.
[http://dx.doi.org/10.1111/j.1463-1318.2008.01638.x] [PMID: 18637932]
[3]
Ratto C. THD Doppler procedure for hemorrhoids: The surgical technique. Tech Coloproctol 2014; 18(3): 291-8.
[http://dx.doi.org/10.1007/s10151-013-1062-3] [PMID: 24026315]
[4]
Scheyer M, Antonietti E, Rollinger G, Mall H, Arnold S. Doppler-guided hemorrhoidal artery ligation. Am J Surg 2006; 191(1): 89-93.
[http://dx.doi.org/10.1016/j.amjsurg.2005.10.007] [PMID: 16399113]
[5]
Rivadeneira DE, Steele SR, Ternent C, et al. Standards practice task force of the american society of colon and rectal surgeons. Practice parameters for the treatment of hemorrhoids (revised 2010). Dis Colon Rectum 2011; 54: 1059-64.
[http://dx.doi.org/10.1097/DCR.0b013e318225513d] [PMID: 21825884]
[6]
Gallo G, Martellucci J, Sturiale A, et al. Consensus statement of the Italian society of colorectal surgery (SICCR): Management and treatment of hemorrhoidal disease. Tech Coloproctol 2020; 24(2): 145-64.
[http://dx.doi.org/10.1007/s10151-020-02149-1] [PMID: 31993837]
[7]
Thomson WH. The anatomy and nature of piles.The haemorrhoid syndrome Tunbridge Wells: Abacus Press. Tunbridge Wells: Abacus Press 1981.
[8]
Shafik A. Surgical anatomy of hemorrhoids.Surgical treatment of hemorrhoids London: Springer . London: Springer 2009.
[http://dx.doi.org/10.1007/978-1-84800-314-9_2]
[9]
Schuurman JP, Go PM, Bleys RL. Anatomical branches of the superior rectal artery in the distal rectum. Colorectal Dis 2009; 11(9): 967-71.
[http://dx.doi.org/10.1111/j.1463-1318.2008.01729.x] [PMID: 19175645]
[10]
Ratto C, Parello A, Donisi L, Litta F, Zaccone G, Doglietto GB. Assessment of haemorrhoidal artery network using colour duplex imaging and clinical implications. Br J Surg 2012; 99(1): 112-8.
[http://dx.doi.org/10.1002/bjs.7700] [PMID: 22021046]
[11]
Ratto C, Donisi L, Parello A, Litta F, Zaccone G, De Simone V. ‘Distal Doppler-guided dearterialization’ is highly effective in treating haemorrhoids by transanal haemorrhoidal dearterialization. Colorectal Dis 2012; 14(11): e786-9.
[http://dx.doi.org/10.1111/j.1463-1318.2012.03146.x] [PMID: 22731786]
[12]
Ratto C, Parello A, Donisi L, Litta F, Doglietto GB. Anorectal physiology is not changed following transanal haemorrhoidal dearterialization for haemorrhoidal disease: Clinical, manometric and endosonographic features. Colorectal Dis 2011; 13(8): e243-5.
[http://dx.doi.org/10.1111/j.1463-1318.2011.02665.x] [PMID: 21689336]
[13]
Ratto C, Campennì P, Papeo F, Donisi L, Litta F, Parello A. Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: A single-center study on 1000 consecutive cases and a review of the literature. Tech Coloproctol 2017; 21(12): 953-62.
[http://dx.doi.org/10.1007/s10151-017-1726-5] [PMID: 29170839]
[14]
Aigner F, Bodner G, Gruber H, et al. The vascular nature of hemorrhoids. J Gastrointest Surg 2006; 10(7): 1044-50.
[http://dx.doi.org/10.1016/j.gassur.2005.12.004] [PMID: 16843876]
[15]
Aigner F, Gruber H, Conrad F, et al. Revised morphology and hemodynamics of the anorectal vascular plexus: Impact on the course of hemorrhoidal disease. Int J Colorectal Dis 2009; 24(1): 105-13.
[http://dx.doi.org/10.1007/s00384-008-0572-3] [PMID: 18766355]
[16]
Aigner F, Bonatti H, Peer S, et al. Vascular considerations for stapled haemorrhoidopexy. Colorectal Dis 2010; 12(5): 452-8.
[http://dx.doi.org/10.1111/j.1463-1318.2009.01812.x] [PMID: 19222523]
[17]
Gupta PJ, Kalaskar S, Taori S, Heda PS. Doppler-guided hemorrhoidal artery ligation does not offer any advantage over suture ligation of grade 3 symptomatic hemorrhoids. Tech Coloproctol 2011; 15(4): 439-44.
[http://dx.doi.org/10.1007/s10151-011-0780-7] [PMID: 22033542]
[18]
Schuurman JP, Borel Rinkes IH, Go PM. Hemorrhoidal artery ligation procedure with or without Doppler transducer in grade II and III hemorrhoidal disease: A blinded randomized clinical trial. Ann Surg 2012; 255(5): 840-5.
[http://dx.doi.org/10.1097/SLA.0b013e31824e2bb5] [PMID: 22504188]
[19]
Brown SR, Tiernan JP, Watson AJM, et al. HubBLe Study team. Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): A multicentre, open-label, randomised controlled trial. Lancet 2016; 388(10042): 356-64.
[http://dx.doi.org/10.1016/S0140-6736(16)30584-0] [PMID: 27236344]
[20]
Fujita T. The HubBle trial: A word of caution. Lancet 2016; 388(10063): 2994-5.
[http://dx.doi.org/10.1016/S0140-6736(16)32523-5] [PMID: 27998535]
[21]
Giordano P. The HubBle trial: A word of caution. Lancet 2016; 388(10063): 2995-6.
[http://dx.doi.org/10.1016/S0140-6736(16)32531-4] [PMID: 27998536]
[22]
Ratto C. Hemorrhoids and the recurrent attempts to destroy them. Tech Coloproctol 2017; 21(1): 69-71.
[http://dx.doi.org/10.1007/s10151-016-1569-5] [PMID: 27999954]
[23]
Porrett LJ, Porrett JK, Ho YH. Documented complications of staple hemorrhoidopexy: A systematic review. Int Surg 2015; 100(1): 44-57.
[http://dx.doi.org/10.9738/INTSURG-D-13-00173.1] [PMID: 25594639]
[24]
Sturiale A, Fabiani B, Menconi C, et al. Long-term results after stapled hemorrhoidopexy: A survey study with mean follow-up of 12 years. Tech Coloproctol 2018; 22(9): 689-96.
[http://dx.doi.org/10.1007/s10151-018-1860-8] [PMID: 30288629]
[25]
Efthimiadis C, Kosmidis C, Grigoriou M, et al. The stapled hemorrhoidopexy syndrome: A new clinical entity? Tech Coloproctol 2011; 15(Suppl. 1): S95-9.
[http://dx.doi.org/10.1007/s10151-011-0741-1] [PMID: 21887569]
[26]
Emile SH, Elfeki H, Sakr A, Shalaby M. Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: A systematic review and meta-analysis of randomized clinical trials. Int J Colorectal Dis 2019; 34(1): 1-11.
[http://dx.doi.org/10.1007/s00384-018-3187-3] [PMID: 30421308]
[27]
Xu L, Chen H, Gu Y. Stapled hemorrhoidectomy versus transanal hemorrhoidal dearterialization in the treatment of hemorrhoids: an updated meta-analysis. Surg Laparosc Endosc Percutan Tech 2019; 29(2): 75-81.
[http://dx.doi.org/10.1097/SLE.0000000000000612] [PMID: 30540639]
[28]
Song Y, Chen H, Yang F, Zeng Y, He Y, Huang H. Transanal hemorrhoidal dearterialization versus stapled hemorrhoidectomy in the treatment of hemorrhoids: A PRISMA-compliant updated meta-analysis of randomized control trials. Medicine (Baltimore) 2018; 97(29): e11502.
[http://dx.doi.org/10.1097/MD.0000000000011502] [PMID: 30024532]
[29]
Festen S, van Hoogstraten MJ, van Geloven AA, Gerhards MF. Treatment of grade III and IV haemorrhoidal disease with PPH or THD. A randomized trial on postoperative complications and short-term results. Int J Colorectal Dis 2009; 24(12): 1401-5.
[http://dx.doi.org/10.1007/s00384-009-0803-2] [PMID: 19798507]
[30]
Giordano P, Nastro P, Davies A, Gravante G. Prospective evaluation of stapled haemorrhoidopexy versus transanal haemorrhoidal dearterialisation for stage II and III haemorrhoids: Three-year outcomes. Tech Coloproctol 2011; 15(1): 67-73.
[http://dx.doi.org/10.1007/s10151-010-0667-z] [PMID: 21318581]
[31]
Infantino A, Altomare DF, Bottini C, et al. THD group of the SICCR (Italian Society of Colorectal Surgery). Prospective randomized multicentre study comparing stapler haemorrhoidopexy with Doppler-guided transanal haemorrhoid dearterialization for third-degree haemorrhoids. Colorectal Dis 2012; 14(2): 205-11.
[http://dx.doi.org/10.1111/j.1463-1318.2011.02628.x] [PMID: 21689317]
[32]
Béliard A, Labbé F, de Faucal D, Fabreguette JM, Pouderoux P, Borie F. A prospective and comparative study between stapled hemorrhoidopexy and hemorrhoidal artery ligation with mucopexy. J Visc Surg 2014; 151(4): 257-62.
[http://dx.doi.org/10.1016/j.jviscsurg.2014.03.009] [PMID: 24726856]
[33]
Xu L, Chen H, Lin G, Ge Q, Qi H, He X. Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: A meta-analysis of randomized control trials. Tech Coloproctol 2016; 20(12): 825-33.
[http://dx.doi.org/10.1007/s10151-016-1551-2] [PMID: 27888438]
[34]
Zampieri N, Castellani R, Andreoli R, Geccherle A. Long-term results and quality of life in patients treated with hemorrhoidectomy using two different techniques: Ligasure versus transanal hemorrhoidal dearterialization. Am J Surg 2012; 204(5): 684-8.
[http://dx.doi.org/10.1016/j.amjsurg.2012.01.014] [PMID: 23140829]
[35]
Elmér SE, Nygren JO, Lenander CE. A randomized trial of transanal hemorrhoidal dearterialization with anopexy compared with open hemorrhoidectomy in the treatment of hemorrhoids. Dis Colon Rectum 2013; 56(4): 484-90.
[http://dx.doi.org/10.1097/DCR.0b013e31827a8567] [PMID: 23478616]
[36]
Denoya PI, Fakhoury M, Chang K, Fakhoury J, Bergamaschi R. Dearterialization with mucopexy versus haemorrhoidectomy for grade III or IV haemorrhoids: Short-term results of a double-blind randomized controlled trial. Colorectal Dis 2013; 15(10): 1281-8.
[http://dx.doi.org/10.1111/codi.12303] [PMID: 23711288]
[37]
Denoya P, Tam J, Bergamaschi R. Hemorrhoidal dearterialization with mucopexy versus hemorrhoidectomy: 3-year follow-up assessment of a randomized controlled trial. Tech Coloproctol 2014; 18(11): 1081-5.
[http://dx.doi.org/10.1007/s10151-014-1219-8] [PMID: 25248418]
[38]
De Nardi P, Capretti G, Corsaro A, Staudacher C. A prospective, randomized trial comparing the short- and long-term results of doppler-guided transanal hemorrhoid dearterialization with mucopexy versus excision hemorrhoidectomy for grade III hemorrhoids. Dis Colon Rectum 2014; 57(3): 348-53.
[http://dx.doi.org/10.1097/DCR.0000000000000085] [PMID: 24509458]

© 2024 Bentham Science Publishers | Privacy Policy