Abstract
A radioisotope and its imaging have been powerful tools to explore the mechanism of chemical reaction and the dynamic behavior of trace element in biomolecular science and nuclear medicine. This article reviews some labelled compounds for radiopharmaceuticals in biochemical science and nuclear medicine using short-lived nuclides, the production and applications of “Multitracer” containing carrier-free radionuclides of more than 50 elements and a new radioactive tracer technique coupled with simultaneously imaging of multiple molecules labelled by γ-emitters. In addition, X-ray phase imaging and microscopy technique using synchrotron radiation are introduced.
Keywords: Radioactive tracer, Labelled compounds, Nuclear reaction, Nuclear fragment, Multitracer, Carrier-free, γ-Ray emission imaging (GREI), α-Emitter, Phase-contrast X-ray imaging, Synchrotron radiation.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:Applications of Nuclear Technique to Biological Sciences Labelled Compounds, Radioactive Tracers, and X-Ray Tomography
Volume: 16 Issue: 24
Author(s): Y. Kobayashi
Affiliation:
Keywords: Radioactive tracer, Labelled compounds, Nuclear reaction, Nuclear fragment, Multitracer, Carrier-free, γ-Ray emission imaging (GREI), α-Emitter, Phase-contrast X-ray imaging, Synchrotron radiation.
Abstract: A radioisotope and its imaging have been powerful tools to explore the mechanism of chemical reaction and the dynamic behavior of trace element in biomolecular science and nuclear medicine. This article reviews some labelled compounds for radiopharmaceuticals in biochemical science and nuclear medicine using short-lived nuclides, the production and applications of “Multitracer” containing carrier-free radionuclides of more than 50 elements and a new radioactive tracer technique coupled with simultaneously imaging of multiple molecules labelled by γ-emitters. In addition, X-ray phase imaging and microscopy technique using synchrotron radiation are introduced.
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Cite this article as:
Kobayashi Y., Applications of Nuclear Technique to Biological Sciences Labelled Compounds, Radioactive Tracers, and X-Ray Tomography, Current Topics in Medicinal Chemistry 2016; 16 (24) . https://dx.doi.org/10.2174/1568026616666160413134922
DOI https://dx.doi.org/10.2174/1568026616666160413134922 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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