Acute Renal Failure in Different Malignant Tumors

Title:Acute Renal Failure in Different Malignant Tumors

Volume: 23 Issue: 19

Author(s): Sanja Radojevic-Skodric, Ljiljana Bogdanovic, Milena Jovanovic, Ivana Baralic, Zoran Dzamic, Ron Gordon, Simona Ognjanovic and Gordana Basta-Jovanovic

Affiliation:

Keywords: Acute renal failure, tumor lysis syndrome, hepatocellular carcinoma (HCC), multiple myeloma, lymphoma.

Abstract: Acute renal failure (ARF) represents a severe complication of malignancies, that causes significant morbidity and mortality. ARF is a common part of multiple organ dysfunction in critically ill patients with cancer with reported mortality rates from 72% to 85% in patients who need renal replacement therapy. The pathways leading to ARF in cancer patients are common to the development of ARF in other conditions. However, certain factors leading to the development of ARF may be associated to the tumor or to the tumor therapy. The purpose of this review is to give specific aspects of renal disease in critically ill cancer patients (CICPs), to overview the causes of ARF in CICPs and to describe recent progress in the management of these complications, including treatment toxicity and bone marrow transplantation (BMT). The prevention of ARF is obligatory and therefore the possible treatments of ARF in CICPs are also discussed.

Cite this article as:

Radojevic-Skodric Sanja, Bogdanovic Ljiljana, Jovanovic Milena, Baralic Ivana, Dzamic Zoran, Gordon Ron, Ognjanovic Simona and Basta-Jovanovic Gordana, Acute Renal Failure in Different Malignant Tumors, Current Medicinal Chemistry 2016; 23 (19) . https://dx.doi.org/10.2174/0929867323666160407113245