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Current Cancer Drug Targets

Editor-in-Chief

ISSN (Print): 1568-0096
ISSN (Online): 1873-5576

Review Article

RBM15 Functions in Blood Diseases

Author(s): Mengyu Hu, Yuxia Yang, Zhi Ji and Jianyuan Luo

Volume 16, Issue 7, 2016

Page: [579 - 585] Pages: 7

DOI: 10.2174/1568009616666160112105706

Price: $65

Abstract

RBM15, an RNA-binding protein, plays important roles in the growth and apoptosis of cells, especially blood cells through regulating multiple signal pathways such as Notch and Wnt. An increasing body of evidence has suggested that RBM15 may play a key function on the development of various blood diseases, such as acute/chronic myeloid leukemia and kaposi′s sarcoma. In this review, we will focus on the progress of the association between RBM15 and its related blood diseases.

Keywords: RBM15, blood diseases, function, mechanism.


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