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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Biomimetic Approaches Towards The Synthesis of Complex Dimeric Natural Products

Author(s): Paul A. Stanley, Christian Spiteri, Jonathan C. Moore, Andrew S. Barrow, Pallavi Sharma and John E. Moses

Volume 22, Issue 12, 2016

Page: [1628 - 1657] Pages: 30

DOI: 10.2174/1381612822666160101123106

Price: $65

Abstract

We present a selection of elegant and diverse biomimetic syntheses of complex natural product dimers. The dimerisation pathways discussed encompass the most prevalent strategies, including: Diels-Alder, Aldol, Mannich, conjugate addition, oxidative, radical and photochemical approaches; each underpinned through rational biosynthetic speculation.

Keywords: Biomimetic, dimer, natural product, total synthesis.


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