Abstract
In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Graphical Abstract
Anti-Cancer Agents in Medicinal Chemistry
Title: Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
Volume: 16 Issue: 5
Author(s): Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong-Shin Chang, Kyeong Lee and Yongseok Choi
Affiliation:
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Abstract: In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Export Options
About this article
Cite this article as:
Singh Sarbjit, Goo Jail, Gajulapati Veeraswamy, Chang Tong-Shin, Lee Kyeong and Choi Yongseok, Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold , Anti-Cancer Agents in Medicinal Chemistry 2016; 16 (5) . https://dx.doi.org/10.2174/1871520615666150916091750
DOI https://dx.doi.org/10.2174/1871520615666150916091750 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Prostaglandin E Synthase: A Novel Drug Target for Inflammation and Cancer
Current Pharmaceutical Design Nitrones: A Potential New Alternative as Therapeutic Agents
Current Organic Chemistry Hyaluronic Acid: The Reason for Its Variety of Physiological and Biochemical Functional Properties
Applied Clinical Research, Clinical Trials and Regulatory Affairs Hepatocyte FRS2α is Essential for the Endocrine Fibroblast Growth Factor to Limit the Amplitude of Bile Acid Production Induced by Prandial Activity
Current Molecular Medicine Bevacizumab in Non Small Cell Lung Cancer: Development, Current Status and Issues
Current Medicinal Chemistry Drug Resistance in Renal Tumors of Childhood
Current Pharmaceutical Biotechnology Overcoming Drug Resistance by Enhancing Apoptosis of Tumor Cells
Current Cancer Drug Targets Innovative Erythrocyte-based Carriers for Gene Delivery in Porcine Vascular Smooth Muscle Cells: Basis for Local Therapy to Prevent Restenosis
Cardiovascular & Hematological Disorders-Drug Targets Lymphocyte Biomarkers of Clinical Responses to Adoptive Immunotherapy of Malignant Melanoma
Current Cancer Therapy Reviews Influence of Genomics on Cancer Vaccine Development - from Guess to Prediction
Current Pharmaceutical Design Recent Progress and Related Patents on the Applications of Bone Marrow-Derived Stem/Progenitor Cells in Regenerative Medicine and Cancer Therapies
Recent Patents on Regenerative Medicine Metabolic Control Analysis and its Applications
Current Bioinformatics Immune Checkpoint Inhibitors in Patients with Recurrent Hepatocellular Carcinoma after Liver Transplantation: A Case Report and Literature Review
Current Cancer Drug Targets Diagnosis of Alterations of Serum Calcium Metabolism
Medicinal Chemistry Prognostic Impact of Tissue Inhibitor of Metalloproteinase-1 in Non- Small Cell Lung Cancer: Systematic Review and Meta-Analysis
Current Medicinal Chemistry Irritable Bowel Syndrome: A Clinical Review
Current Rheumatology Reviews Perspectives on Medicinal Properties of Benzoquinone Compounds
Mini-Reviews in Medicinal Chemistry Antitumor Pharmacology - Quo Vadis ?
Current Medicinal Chemistry - Anti-Cancer Agents Targeting Epithelial-Mesenchymal Transition Phenotype for Gastro-Intestinal Cancer
Current Pharmaceutical Design Pretreatment Serum Fibrinogen Levels are Associated with Postoperative Distant Metastasis and Prognosis of Resected Lung Cancer Patient: A Retrospective Study
Current Signal Transduction Therapy