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Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Drug Likeness and Selective Functionalization of Quinoxalines

Author(s): Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery and Giuliano Cesar Clososki

Volume 12, Issue 6, 2015

Page: [714 - 729] Pages: 16

DOI: 10.2174/157017941206150828110053

Price: $65

Abstract

In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.

Keywords: Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.

Graphical Abstract


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