Abstract
Nitrogen heterocyclic N-oxides attract enormous interest in synthetic chemistry, medicinal chemistry, functional materials and energetic materials. Cyclization reaction turns out to be an important and highly rewarding protocol for the construction of N-heterocyclic N-oxides and different types of organonitrogen compound could be utilized as crude materials. In this work a review of recent advancement in the generation of pyrazole, imidazole, triazole, triazine, tetrazine, isoquinoline and other N-heterocyclic N-oxides and their derivatives via cyclization reactions is presented.
Keywords: Nitrogen heterocyclic N-oxides, cyclization, mechanism, synthesis.
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Current Organic Chemistry
Title:Cyclization: A Useful Approach for the Synthesis of Nitrogen Heterocyclic N-Oxides
Volume: 19 Issue: 19
Author(s): Ning Liu, Yuan-Jie Shu, Bo-Zhou Wang, Xiang-Zhi Li and Fu-Qiang Bi
Affiliation:
Keywords: Nitrogen heterocyclic N-oxides, cyclization, mechanism, synthesis.
Abstract: Nitrogen heterocyclic N-oxides attract enormous interest in synthetic chemistry, medicinal chemistry, functional materials and energetic materials. Cyclization reaction turns out to be an important and highly rewarding protocol for the construction of N-heterocyclic N-oxides and different types of organonitrogen compound could be utilized as crude materials. In this work a review of recent advancement in the generation of pyrazole, imidazole, triazole, triazine, tetrazine, isoquinoline and other N-heterocyclic N-oxides and their derivatives via cyclization reactions is presented.
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Cite this article as:
Liu Ning, Shu Yuan-Jie, Wang Bo-Zhou, Li Xiang-Zhi and Bi Fu-Qiang, Cyclization: A Useful Approach for the Synthesis of Nitrogen Heterocyclic N-Oxides, Current Organic Chemistry 2015; 19 (19) . https://dx.doi.org/10.2174/1385272819666150622174626
DOI https://dx.doi.org/10.2174/1385272819666150622174626 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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