Abstract
The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.
Keywords: Antibacterial, Antiviral, Drug-multiresistant bacteria, Molecular mechanism.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles
Volume: 15 Issue: 16
Author(s): Faik N. Oktar, Mehmet Yetmez, Denisa Ficai, Anton Ficai, Florica Dumitru and Alexandra Pica
Affiliation:
Keywords: Antibacterial, Antiviral, Drug-multiresistant bacteria, Molecular mechanism.
Abstract: The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.
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Cite this article as:
Oktar N. Faik, Yetmez Mehmet, Ficai Denisa, Ficai Anton, Dumitru Florica and Pica Alexandra, Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles, Current Topics in Medicinal Chemistry 2015; 15 (16) . https://dx.doi.org/10.2174/1568026615666150414141601
DOI https://dx.doi.org/10.2174/1568026615666150414141601 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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