Abstract
A new one-pot three-component and highly efficient approach for the synthesis of quinoxaline derivatives was investigated. This was achieved via two methods from the reaction of α-hydroxy ketones or 1,2-dicarbonyl compounds with o-phenylenediamine in the presence of catalytic amount of many metal salt catalysts especially Zn(OAc)2 and mixture of Mn(OAc)2 and Zn(OAc)2.
Keywords: Quinoxaline, 1, 2-dicarbonyl compounds, α-hydroxyketone, metal salts, in-Situ oxidation, one-pot procedure.
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Letters in Organic Chemistry
Title:A Comprehensive Comparison Metal Salts Effect on Time and Yield of Quinoxalines Synthesis
Volume: 12 Issue: 1
Author(s): Ardeshir Khazaei, Heidar Ali Alavi Nik and Payam Rahmani
Affiliation:
Keywords: Quinoxaline, 1, 2-dicarbonyl compounds, α-hydroxyketone, metal salts, in-Situ oxidation, one-pot procedure.
Abstract: A new one-pot three-component and highly efficient approach for the synthesis of quinoxaline derivatives was investigated. This was achieved via two methods from the reaction of α-hydroxy ketones or 1,2-dicarbonyl compounds with o-phenylenediamine in the presence of catalytic amount of many metal salt catalysts especially Zn(OAc)2 and mixture of Mn(OAc)2 and Zn(OAc)2.
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Cite this article as:
Khazaei Ardeshir, Alavi Nik Ali Heidar and Rahmani Payam, A Comprehensive Comparison Metal Salts Effect on Time and Yield of Quinoxalines Synthesis, Letters in Organic Chemistry 2015; 12 (1) . https://dx.doi.org/10.2174/1570178612666141211224503
DOI https://dx.doi.org/10.2174/1570178612666141211224503 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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