Development Course and an Application Strategy for Induced Pluripotent Stem Cells in Regenerative Medicine

Title:Development Course and an Application Strategy for Induced Pluripotent Stem Cells in Regenerative Medicine

Volume: 9 Issue: 3

Author(s): Yuanzhi Xu, Jing Wang, Runyi Mao, Xiaoshan Tang, Renhuan Huang, Raorao Wang and Yunfeng Lin

Affiliation:

Keywords: Application, degenerative disease, differentiation, epigenetic regulation, induced pluripotent stem cells, regenerative medicine.

Abstract: In 2006, Takahashi and Yamanaka first established induced pluripotent stem cells (iPScs). Since then, numerous improvements have been made in the fields of stem cell research, drug research, modelling of diseases, and the treatment of degenerative diseases. Recently, there has been increasing research involving small molecules for evaluating the efficiency of iPSc generation and reducing the risks of heredity as well as oncogenous problems. However, the molecular mechanisms of iPScs remain to be further explored, to meet the demands of practical applications. With a better understanding of degenerative diseases, more complex treatment strategies for novel regenerative medicine are anticipated, and iPSc technology offers an available pathway. This review focuses on the development and application of iPScs.

Cite this article as:

Xu Yuanzhi, Wang Jing, Mao Runyi, Tang Xiaoshan, Huang Renhuan, Wang Raorao and Lin Yunfeng, Development Course and an Application Strategy for Induced Pluripotent Stem Cells in Regenerative Medicine, Current Stem Cell Research & Therapy 2014; 9 (3) . https://dx.doi.org/10.2174/1574888X09666140213202227