Abstract
1,2,4-Triazine nucleus is a prominent structural core system present in numerous pharmacologically active compounds. Till date, various 1,2,4-triazine analogs, possesing a wide range of potent pharmacological activities, have been reported. This review is an attempt to compile the medicinal chemistry aspects of various synthesized 1,2,4-triazine analogs reported so far.
Keywords: Anticancer activity, anticonvulsant activity, antimicrobial activity, 1, 2, 4-triazine.
Mini-Reviews in Medicinal Chemistry
Title:1,2,4-Triazine Analogs as Novel Class of Therapeutic Agents
Volume: 14 Issue: 2
Author(s): Rajeev Kumar, T.S. Sirohi, Hariram Singh, Ramji Yadav, R.K. Roy, A. Chaudhary and S.N. Pandeya
Affiliation:
Keywords: Anticancer activity, anticonvulsant activity, antimicrobial activity, 1, 2, 4-triazine.
Abstract: 1,2,4-Triazine nucleus is a prominent structural core system present in numerous pharmacologically active compounds. Till date, various 1,2,4-triazine analogs, possesing a wide range of potent pharmacological activities, have been reported. This review is an attempt to compile the medicinal chemistry aspects of various synthesized 1,2,4-triazine analogs reported so far.
Export Options
About this article
Cite this article as:
Kumar Rajeev, Sirohi T.S., Singh Hariram, Yadav Ramji, Roy R.K., Chaudhary A. and Pandeya S.N., 1,2,4-Triazine Analogs as Novel Class of Therapeutic Agents, Mini-Reviews in Medicinal Chemistry 2014; 14 (2) . https://dx.doi.org/10.2174/1389557514666140131111837
DOI https://dx.doi.org/10.2174/1389557514666140131111837 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Potential for Genetically Altered Microglia to Influence Glioma Treatment
CNS & Neurological Disorders - Drug Targets Pleiotrophin as a Possible New Target for Angiogenesis-Related Diseases and Cancer
Recent Patents on Anti-Cancer Drug Discovery MicroRNA-mediated Regulation of Angiogenesis
Current Angiogenesis (Discontinued) In Vitro Models of the Blood-Brain Barrier: When to Use Which?
Current Medicinal Chemistry - Central Nervous System Agents Notch Signalling Pathways and Their Importance in the Treatment of Cancers
Current Drug Targets The Biological Role of mTOR in the Pathogenesis of Solid Tumors: An Overview
Current Enzyme Inhibition Molecular Aspects of FKBP51 that Enable Melanoma Dissemination
Current Molecular Pharmacology Recent Progress in Discovery and Development of Antimitotic Agents
Anti-Cancer Agents in Medicinal Chemistry A Nanoparticle-Encapsulated Non-Nucleoside Reverse-Transcriptase Inhibitor with Enhanced Anti-HIV-1 Activity and Prolonged Circulation Time in Plasma
Current Pharmaceutical Design Basis for the Application of Analytical Models of the Bloch NMR Flow Equations for Functional Magnetic Resonance Imaging (fMRI): A Review
Recent Patents on Medical Imaging Meet Our Co-Editor
Current Signal Transduction Therapy <i>Circular RNA NF1-419</i> Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells
Recent Patents on Anti-Cancer Drug Discovery Melanocortins As Innovative Drugs for Ischemic Diseases and Neurodegenerative Disorders: Established Data and Perspectives
Current Medicinal Chemistry Current Development in Encapsulated Cell Therapy for Degenerative Retinopathies
Current Tissue Engineering (Discontinued) The FDG-PET Revolution of Medical Imaging – Four Decades and Beyond
Current Molecular Imaging (Discontinued) Apoptosis Signaling Pathways in Anticancer Therapy
Current Cancer Therapy Reviews Longitudinal Melatonin Production in Female Laboratory Rats During 1997-2006: Possible Modulatory Effects of Changing Solar Activity
Current Aging Science Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9
Letters in Drug Design & Discovery Glioma Stem Cell Maintenance: The Role of the Microenvironment
Current Pharmaceutical Design Human Galectin-3 Selective and High Affinity Inhibitors. Present State and Future Perspectives
Current Medicinal Chemistry