Abstract
Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function, release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory mechanisms in MI.
Keywords: Cell-free DNA, biological characteristics, methodology, myocardial infarction.
Current Pharmaceutical Design
Title:Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction
Volume: 19 Issue: 28
Author(s): Rongrong Jing, Ming Cui, Huimin Wang and Shaoqing Ju
Affiliation:
Keywords: Cell-free DNA, biological characteristics, methodology, myocardial infarction.
Abstract: Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function, release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory mechanisms in MI.
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Cite this article as:
Jing Rongrong, Cui Ming, Wang Huimin and Ju Shaoqing, Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction, Current Pharmaceutical Design 2013; 19 (28) . https://dx.doi.org/10.2174/1381612811319280012
DOI https://dx.doi.org/10.2174/1381612811319280012 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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