Abstract
Humans and animals are unable to synthesize essential amino acids such as branch chain amino acids methionine (Met), lysine (Lys) and tryptophan (Trp). Therefore, these amino acids need to be supplied through the diets. Several essential amino acids are deficient or completely lacking among crops used for human food and animal feed. For example, soybean is deficient in Met; Lys and Trp are lacking in maize. In this mini review, we will first summarize the roles of essential amino acids in animal nutrition. Next, we will address the question: “What are the amino acids deficient in various plants and their biosynthesis pathways?” And: “What approaches are being used to improve the availability of essential amino acids in plants?” The potential targets for metabolic engineering will also be discussed, including what has already been done and what remains to be tested.
Keywords: Protein nutritional quality, Essential amino acids, Lysine, Methionine, Tryptophan, Genetic engineering.
Graphical Abstract
Current Genomics
Title:Improving Nutritional Quality of Plant Proteins Through Genetic Engineering
Volume: 17 Issue: 3
Author(s): Dung Tien Lea, Ha Duc Chua and Ngoc Quynh Lea
Affiliation:
Keywords: Protein nutritional quality, Essential amino acids, Lysine, Methionine, Tryptophan, Genetic engineering.
Abstract: Humans and animals are unable to synthesize essential amino acids such as branch chain amino acids methionine (Met), lysine (Lys) and tryptophan (Trp). Therefore, these amino acids need to be supplied through the diets. Several essential amino acids are deficient or completely lacking among crops used for human food and animal feed. For example, soybean is deficient in Met; Lys and Trp are lacking in maize. In this mini review, we will first summarize the roles of essential amino acids in animal nutrition. Next, we will address the question: “What are the amino acids deficient in various plants and their biosynthesis pathways?” And: “What approaches are being used to improve the availability of essential amino acids in plants?” The potential targets for metabolic engineering will also be discussed, including what has already been done and what remains to be tested.
Export Options
About this article
Cite this article as:
Tien Lea Dung, Duc Chua Ha and Quynh Lea Ngoc, Improving Nutritional Quality of Plant Proteins Through Genetic Engineering, Current Genomics 2016; 17 (3) . https://dx.doi.org/10.2174/1389202917666160202215934
DOI https://dx.doi.org/10.2174/1389202917666160202215934 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
Call for Papers in Thematic Issues
Current Genomics in Cardiovascular Research
Cardiovascular diseases are the main cause of death in the world, in recent years we have had important advances in the interaction between cardiovascular disease and genomics. In this Research Topic, we intend for researchers to present their results with a focus on basic, translational and clinical investigations associated with ...read more
Deep learning in Single Cell Analysis
The field of biology is undergoing a revolution in our ability to study individual cells at the molecular level, and to integrate data from multiple sources and modalities. This has been made possible by advances in technologies for single-cell sequencing, multi-omics profiling, spatial transcriptomics, and high-throughput imaging, as well as ...read more
New insights on Pediatric Tumors and Associated Cancer Predisposition Syndromes
Because of the broad spectrum of children cancer susceptibility, the diagnosis of cancer risk syndromes in children is rarely used in direct cancer treatment. The field of pediatric cancer genetics and genomics will only continue to expand as a result of increasing use of genetic testing tools. It's possible that ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration
Current Topics in Medicinal Chemistry Small Transthyretin (TTR) Ligands as Possible Therapeutic Agents in TTR Amyloidoses
Current Drug Targets - CNS & Neurological Disorders Chromogranin-A: A Multifaceted Cardiovascular Role in Health and Disease
Current Medicinal Chemistry TTR Fibril Formation Inhibitors: Is there a SAR?
Current Medicinal Chemistry Fitness or Fatness: The Debate Continues for AMP-Activated Protein Kinase in Heart Function
Current Cardiology Reviews The LIM Protein fhlA is Essential for Heart Chamber Development in Zebrafish Embryos
Current Molecular Medicine Acute Respiratory Failure in Obstetric Patients
Current Women`s Health Reviews Atrial Remodeling and Novel Pharmacological Strategies for Antiarrhythmic Therapy in Atrial Fibrillation
Current Medicinal Chemistry Control of Menopausal Transition through Physical Exercises
Current Women`s Health Reviews Cellular Therapy for Myocardial Repair
Current Cardiology Reviews Therapeutic Potential and Mechanisms of Action of Mesenchymal Stromal Cells for Acute Respiratory Distress Syndrome
Current Stem Cell Research & Therapy How to Recognize Epicardial Origin of Ventricular Tachycardias?
Current Cardiology Reviews Cardiac Toxicity of Antineoplastic Anthracyclines
Current Medicinal Chemistry - Anti-Cancer Agents Mechanisms and Medical Management of Exercise Intolerance in Hypertrophic Cardiomyopathy
Current Pharmaceutical Design New Therapeutic Applications of Phosphodiesterase 5 Inhibitors (PDE5-Is)
Current Medicinal Chemistry The Evolving Therapy of Rheumatic Diseases, The Future is Now
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Re-Wiring the Circuit: Mitochondria as a Pharmacological Target in Liver Disease
Current Medicinal Chemistry Clinical Pharmacogenetics and Potential Application in Personalized Medicine
Current Drug Metabolism Cardiac Calmodulin Kinase: A Potential Target for Drug Design
Current Medicinal Chemistry Decoding the Transcriptional Response to Ischemic Stroke in Obese and Non-obese Mice Brain
Current Neurovascular Research