Invasive Aspergillosis in Children and Adolescents

Title:Invasive Aspergillosis in Children and Adolescents

Volume: 19 Issue: 20

Author(s): Andreas H. Groll, Dominik Schrey, Athanasios Tragiannidis, Konrad Bochennek and Thomas Lehrnbecher

Affiliation:

Keywords: Mycoses, aspergillosis, children, adolescents, cancer, bone marrow transplantation, solid organ transplantation, immunodeficiency.

Abstract: Invasive aspergillosis is an important cause of morbidity and mortality in immunocompromised children. Disease control depends on prevention, early diagnosis, predictive microbiological information, prompt and appropriate treatment and restoration of host defenses. Relative to adults, invasive aspergillosis in children and adolescents is unique in its clinical presentation, epidemiology, and in particular, the utility of newer diagnostic tools and the pharmacokinetics of active antifungal agents. Here we review the presentation and epidemiology of invasive aspergillosis in children and adolescents and discuss the value of current diagnostic tools and strategies and options for treatment and prevention in this special population.

Cite this article as:

Groll Andreas H., Schrey Dominik, Tragiannidis Athanasios, Bochennek Konrad and Lehrnbecher Thomas, Invasive Aspergillosis in Children and Adolescents, Current Pharmaceutical Design 2013; 19 (20) . https://dx.doi.org/10.2174/13816128113199990311