Bone Metastases Radiopharmaceuticals: An Overview

Title:Bone Metastases Radiopharmaceuticals: An Overview

Volume: 6 Issue: 1

Author(s): Vincenzo Cuccurullo, Giuseppe Lucio Cascini, Oscar Tamburrini, Antonio Rotondo and Luigi Mansi

Affiliation:

Keywords: Bone metastases, Bone scintigraphy, Tc-99m diphosphonates, F-18 fluoride, F-18 Fluoro-deoxyglucose, Oncotropic radio-agents

Abstract: The skeleton is one of the preferential sites for metastases of solid tumors, and metastatic disease is the most common malignancy of the bone. Diagnosis and evaluation of skeletal metastases require more frequently a combined approach of different diagnostic methods. Between the currently available imaging modalities, a major role is devoted to two radionuclide functional techniques namely scintigraphy and positron emission tomography (PET) imaging. Both these techniques require the use of different radiopharmaceuticals. The aim of this paper is to review the most important radiocompounds that can be successfully used to detect and/or characterize bone metastases.

Cite this article as:

Cuccurullo Vincenzo, Lucio Cascini Giuseppe, Tamburrini Oscar, Rotondo Antonio and Mansi Luigi, Bone Metastases Radiopharmaceuticals: An Overview, Current Radiopharmaceuticals 2013; 6 (1) . https://dx.doi.org/10.2174/1874471011306010007