A Critical Analysis on the Impact of Antiplatelet Therapy in the Patency of Infrainguinal Bypass Grafts

Title:A Critical Analysis on the Impact of Antiplatelet Therapy in the Patency of Infrainguinal Bypass Grafts

Volume: 11 Issue: 1

Author(s): George S. Sfyroeras, Vassileios Saleptsis, Christos Argyriou, Georgios A. Antoniou, Frans L. Moll and Athanasios D. Giannoukas

Affiliation:

Keywords: Antiplatelet agents, peripheral arterial disease, infrainguinal bypass, graft patency, aspirin, clopidogrel, ticlopidine, ticlopidine, Lower limb atherosclerosis, femoropopliteal

Abstract: Antiplatelet therapy plays an important role in the management of atherosclerotic disease and numerous studies have shown their efficacy in the reduction of cardiovascular mortality and morbidity. Antiplatelets are given in patients subjected to lower limb bypass aiming not only to reduce cardiovascular mortality and morbidity but also improve graft patency. Various antiplatelet agents have been used for this purpose. The aim of this review article is to critically evaluate the existing evidence on the impact of antiplatelet therapy for maintaining infrainguinal graft patency and highlight the mechanisms involved along these lines.

Cite this article as:

S. Sfyroeras George, Saleptsis Vassileios, Argyriou Christos, A. Antoniou Georgios, L. Moll Frans and D. Giannoukas Athanasios, A Critical Analysis on the Impact of Antiplatelet Therapy in the Patency of Infrainguinal Bypass Grafts, Current Vascular Pharmacology 2013; 11 (1) . https://dx.doi.org/10.2174/1570161111309010047