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Review Article

胸腺素β4:在心脏损伤中的多面组织修复刺激蛋白

卷 27, 期 37, 2020

页: [6294 - 6305] 页: 12

弟呕挨: 10.2174/0929867326666190716125456

价格: $65

摘要

胸腺素β-4 (Tβ4)是一种主要的多效性肌动蛋白隔离蛋白，参与肿瘤的发生。Tβ4是一种水溶性蛋白，在心肌梗死、脑卒中后组织重塑和溃疡修复、周围神经系统(PNS)和中枢神经系统(CNS)的可塑性和神经血管重塑等方面具有不同的临床应用前景。另一方面，Tβ4在包括心肌组织在内的其他组织中也有类似的作用。在最近的报道中，Tβ4被认为是心肌细胞存活的促进因子，因为它激活了常驻心外膜祖细胞，并调节炎症引起的损伤。此外，Tβ4可能在骨骼肌和不同器官中发挥作用，并与许多其他组织修复刺激因子，包括褪黑素和c纤维衍生肽协同作用。基于这些原因，本文强调了Tβ4在心脏愈合中的重要作用。

关键词: 组织修复，胸腺素- 4，褪黑素，C纤维衍生肽，外周神经系统，中枢神经系统

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