摘要
几十年来,世界各地的科学家根据对癌症患者饮食中使用的水果和蔬菜的影响的流行病学观察,研究了氧化损伤与癌症之间的强烈相互关系。据报道,维生素C,维生素D和维生素E主要参与改善肺癌,胃癌,前列腺癌,结直肠癌,头颈癌和癌症的化学疗法和放射疗法中的副作用。发现作为抗氧化剂佐剂的维生素具有凋亡和抗血管生成潜力以及抑制癌细胞转移的作用。本章明确讨论维生素与癌症预防和治疗有关的主要方面。参考最近的研究报告,它描述了维生素及其天然资源,维生素在体内的作用,维生素作为饮食中的主要成分及其对癌症生物学的影响。此外,本文还包括药物研究进展,提高维生素对癌症患者生物利用度的安全性和有效性。临床医生和研究人员必须仔细考虑个别癌症患者的营养需求,以便治疗癌症并提高预期寿命。
关键词: 维生素,癌症,预防,治疗,饮食,新陈代谢,瞄准。
Current Molecular Medicine
Title:Vitamins for Cancer Prevention and Treatment: An Insight
Volume: 17 Issue: 5
关键词: 维生素,癌症,预防,治疗,饮食,新陈代谢,瞄准。
摘要: Over a few decades a strong interlink between oxidative damage and cancer has been investigated by various scientists across the world on the basis of epidemiological observations of the effects of fruits and vegetables used in the diet for cancer patients. Primarily, Vitamin C, Vitamin D and Vitamin E are reported to be involved in the amelioration of side effects which occur in chemotherapy and radiation therapy of lungs, stomach, prostate, colorectal, gastric head and neck cancers. The vitamins acting as antioxidant adjuvants are found to have apoptotic and antiangiogenesis potential as well as inhibitory effects against metastasis in cancer cells. This chapter explicitly discusses the key aspects concerned with the vitamins in relation to cancer prevention and treatment. It describes vitamins and their natural resources, role of vitamins in the body, and vitamins as prime ingredients in the diet and their effects on cancer biology with reference to recent research reports. Moreover, this paper also includes the emerging potential of pharmaceutical advances to enhance bioavailability of the vitamins to cancer patients with improved safety and efficacy. Clinicians and researchers must mull over the nutritional requirements of individual cancer patient so as to treat cancer and increase life expectancy.
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Cite this article as:
Vitamins for Cancer Prevention and Treatment: An Insight, Current Molecular Medicine 2017; 17 (5) . https://dx.doi.org/10.2174/1566524018666171205113329
DOI https://dx.doi.org/10.2174/1566524018666171205113329 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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